PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26825997-7 2016 In endothelium-denuded preparations, relaxation to ACh (1 nmol) disappeared, but ACh at 10 and 100 nmol caused long-lasting vasodilatations, which were markedly blocked by the treatment of pirenzepine (M1 antagonist) or 4-DAMP (M1 and M3 antagonist) plus hexamethonium (nicotinic AChR antagonist), but not methoctramine (M2 and M4 antagonist). Pirenzepine 189-200 cholinergic receptor nicotinic alpha 2 subunit Rattus norvegicus 280-284