PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24916315-4 2014 Mechanism studies revealed that T cell-derived IFN-gamma and CD40 ligand (CD40L) induced the expression of indoleamine 2,3-dioxygenase (IDO) in OCs, which mediated the immunosuppressive function on T-cell proliferation through depleting tryptophan. Tryptophan 237-247 CD40 ligand Homo sapiens 61-72 31896599-8 2020 Unexpectedly, the ALVAC-SIV/CD40L vector had a blunting effect on CD4+ Th1 helper responses, and instead favored the induction of myeloid derived suppressor cells, the immune-suppressive IL-10 cytokine, and the down-modulatory tryptophan catabolism. Tryptophan 227-237 CD40 ligand Homo sapiens 28-33 23010537-6 2015 This nonsense mutation predicted a tryptophan codon (TGG) change to a stop codon (TGA) at position 140 (W140X), preventing CD40L protein expression. Tryptophan 35-45 CD40 ligand Homo sapiens 123-128 24916315-4 2014 Mechanism studies revealed that T cell-derived IFN-gamma and CD40 ligand (CD40L) induced the expression of indoleamine 2,3-dioxygenase (IDO) in OCs, which mediated the immunosuppressive function on T-cell proliferation through depleting tryptophan. Tryptophan 237-247 CD40 ligand Homo sapiens 74-79 24924152-1 2014 CD40/CD40-ligand (CD40L) signalling is a key stimulatory pathway which triggers the tryptophan (Trp) catabolizing enzyme IDO in dendritic cells and is immunosuppressive in cancer. Tryptophan 84-94 CD40 ligand Homo sapiens 5-16 24924152-1 2014 CD40/CD40-ligand (CD40L) signalling is a key stimulatory pathway which triggers the tryptophan (Trp) catabolizing enzyme IDO in dendritic cells and is immunosuppressive in cancer. Tryptophan 84-94 CD40 ligand Homo sapiens 18-23 24924152-1 2014 CD40/CD40-ligand (CD40L) signalling is a key stimulatory pathway which triggers the tryptophan (Trp) catabolizing enzyme IDO in dendritic cells and is immunosuppressive in cancer. Tryptophan 96-99 CD40 ligand Homo sapiens 5-16 24924152-1 2014 CD40/CD40-ligand (CD40L) signalling is a key stimulatory pathway which triggers the tryptophan (Trp) catabolizing enzyme IDO in dendritic cells and is immunosuppressive in cancer. Tryptophan 96-99 CD40 ligand Homo sapiens 18-23