PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25644787-6 2015 In addition, mRNA and protein levels of Akt were increased significantly in the PCB118-treated groups, whereas FoxO3a expression did not show particular variation. 2,3',4,4',5-pentachlorobiphenyl 80-86 AKT serine/threonine kinase 1 Homo sapiens 40-43 25644787-7 2015 Furthermore, exposure to PCB118 was associated with a significant increase of the protein levels of p-Akt and p-FoxO3a, and these effects were blocked by LY294002. 2,3',4,4',5-pentachlorobiphenyl 25-31 AKT serine/threonine kinase 1 Homo sapiens 102-105 25644787-10 2015 Our research suggests that PCB118 may induce thyrocyte dysfunction through the Akt/FoxO3a/NIS signalling pathway, which provides potential new insights for finding interventions to counteract the damage to the human body caused by PCBs. 2,3',4,4',5-pentachlorobiphenyl 27-33 AKT serine/threonine kinase 1 Homo sapiens 79-82