PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26519956-0	2016	2,3",4,4",5-Pentachlorobiphenyl Induces Inflammatory Responses in the Thyroid Through JNK and Aryl Hydrocarbon Receptor-Mediated Pathway.	2,3',4,4',5-pentachlorobiphenyl	0-31	aryl hydrocarbon receptor	Rattus norvegicus	94-119	
26519956-5	2016	Moreover, stimulation with PCB118 resulted in the upregulation of the aryl hydrocarbon receptor (AhR)-responsive gene cytochrome P450 1A1 in FRTL-5 cells; whereas pretreatment with the AhR inhibitor alpha-naphthoflavone or AhR small interfering RNA (siRNA) suppressed AhR, CYP1A1, IL-6, and ICAM-1 and restored NIS expression.	2,3',4,4',5-pentachlorobiphenyl	27-33	aryl hydrocarbon receptor	Rattus norvegicus	185-188	
26519956-5	2016	Moreover, stimulation with PCB118 resulted in the upregulation of the aryl hydrocarbon receptor (AhR)-responsive gene cytochrome P450 1A1 in FRTL-5 cells; whereas pretreatment with the AhR inhibitor alpha-naphthoflavone or AhR small interfering RNA (siRNA) suppressed AhR, CYP1A1, IL-6, and ICAM-1 and restored NIS expression.	2,3',4,4',5-pentachlorobiphenyl	27-33	aryl hydrocarbon receptor	Rattus norvegicus	185-188	
26519956-5	2016	Moreover, stimulation with PCB118 resulted in the upregulation of the aryl hydrocarbon receptor (AhR)-responsive gene cytochrome P450 1A1 in FRTL-5 cells; whereas pretreatment with the AhR inhibitor alpha-naphthoflavone or AhR small interfering RNA (siRNA) suppressed AhR, CYP1A1, IL-6, and ICAM-1 and restored NIS expression.	2,3',4,4',5-pentachlorobiphenyl	27-33	aryl hydrocarbon receptor	Rattus norvegicus	185-188	
26519956-7	2016	Altogether, PCB118 stimulates production of IL-6, TNF-alpha, and ICAM-1 in the thyroid through AhR and JNK activations and subsequently interferes with NIS expression, resulting in the disruption of thyroid structure and function.	2,3',4,4',5-pentachlorobiphenyl	12-18	aryl hydrocarbon receptor	Rattus norvegicus	95-98