PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31251971-7 2019 Furthermore, we found that PCB118 activated NADPH oxidase through the aryl hydrocarbon receptor (AhR) in SMMC-7721 cells. 2,3',4,4',5-pentachlorobiphenyl 27-33 aryl hydrocarbon receptor Homo sapiens 70-95 31251971-7 2019 Furthermore, we found that PCB118 activated NADPH oxidase through the aryl hydrocarbon receptor (AhR) in SMMC-7721 cells. 2,3',4,4',5-pentachlorobiphenyl 27-33 aryl hydrocarbon receptor Homo sapiens 97-100 31251971-8 2019 Consistently, treatment with AhR shRNA suppressed PCB118-induced effects on PKM2, cell proliferation and glycolysis. 2,3',4,4',5-pentachlorobiphenyl 50-56 aryl hydrocarbon receptor Homo sapiens 29-32 31251971-9 2019 Overall, these results indicated that PCB118 promotes HCC cell proliferation via PKM2-dependent upregulation of glycolysis, which is mediated by AhR/NADPH oxidase-induced ROS production. 2,3',4,4',5-pentachlorobiphenyl 38-44 aryl hydrocarbon receptor Homo sapiens 145-148 26519956-5 2016 Moreover, stimulation with PCB118 resulted in the upregulation of the aryl hydrocarbon receptor (AhR)-responsive gene cytochrome P450 1A1 in FRTL-5 cells; whereas pretreatment with the AhR inhibitor alpha-naphthoflavone or AhR small interfering RNA (siRNA) suppressed AhR, CYP1A1, IL-6, and ICAM-1 and restored NIS expression. 2,3',4,4',5-pentachlorobiphenyl 27-33 aryl hydrocarbon receptor Homo sapiens 70-95 26519956-5 2016 Moreover, stimulation with PCB118 resulted in the upregulation of the aryl hydrocarbon receptor (AhR)-responsive gene cytochrome P450 1A1 in FRTL-5 cells; whereas pretreatment with the AhR inhibitor alpha-naphthoflavone or AhR small interfering RNA (siRNA) suppressed AhR, CYP1A1, IL-6, and ICAM-1 and restored NIS expression. 2,3',4,4',5-pentachlorobiphenyl 27-33 aryl hydrocarbon receptor Homo sapiens 97-100