PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2424829-1 1986 The effects of Isoprinosine (ISO) on interleukin-2 (IL-2) production by human peripheral blood mononuclear cells (PBMC) were investigated. Inosine Pranobex 29-32 interleukin 2 Homo sapiens 37-50 2424829-0 1986 Effect of isoprinosine on sialylation of interleukin-2. Inosine Pranobex 10-22 interleukin 2 Homo sapiens 41-54 2469797-0 1988 Isoprinosine potentiation of human peripheral blood mononuclear cell response to mitogens: kinetics and effect on expression of the IL-2 receptor and the activity of interleukin 2. Inosine Pranobex 0-12 interleukin 2 Homo sapiens 166-179 2469797-4 1988 Increased interleukin-2 activity was detected in three out of nine supernatants from PHA activated mononuclear cells which were cultured in the presence of isoprinosine. Inosine Pranobex 156-168 interleukin 2 Homo sapiens 10-23 6207122-1 1984 Isoprinosine appeared to potentiate the production of interleukin 1 and interleukin 2 in cultures of lipopolysaccharide stimulated human monocytes and phytohemagglutinin stimulated cultures of blood mononuclear cells respectively at pharmacological drug levels. Inosine Pranobex 0-12 interleukin 2 Homo sapiens 72-85 2409037-6 1985 In the presence of ISO, ConA-induced lymphocyte proliferation, NK activity, neutrophil chemotaxis, and IL-2 production were restored to normal or near normal levels in 50 of the 55 (90.0%), 35 of the 41 (85.3%), 44 of the 52 (84.6%), and 25 of the 35 (71.4%) aging humans, respectively. Inosine Pranobex 19-22 interleukin 2 Homo sapiens 103-107 2581997-0 1985 Partial restoration of impaired interleukin-2 production and Tac antigen (putative interleukin-2 receptor) expression in patients with acquired immune deficiency syndrome by isoprinosine treatment in vitro. Inosine Pranobex 174-186 interleukin 2 Homo sapiens 32-45 2581997-0 1985 Partial restoration of impaired interleukin-2 production and Tac antigen (putative interleukin-2 receptor) expression in patients with acquired immune deficiency syndrome by isoprinosine treatment in vitro. Inosine Pranobex 174-186 interleukin 2 Homo sapiens 83-96 6190598-8 1983 The mechanism responsible for these effects is not known but IL-2 production by patient lymphocytes in vitro which was low for both RA (P less than 0.01) and SLE (P less than 0.02) increased significantly (P less than 0.05) when SLE lymphocytes were cultured with IPS. Inosine Pranobex 264-267 interleukin 2 Homo sapiens 61-65