PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26153065-1	2015	Buprenorphine, a maintenance drug for heroin addicts, exerts its pharmacological function via kappa- (KOP), mu-opioid (MOP) and nociceptin/opioid receptor-like 1 (NOP) receptors.	Buprenorphine	0-13	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	102-105	
26153065-8	2015	Chronic exposure to buprenorphine induced concentration-dependent AC superactivation in cells expressing KOP+NOP receptors, and the level of this superactivation was even higher in KOP+MOP+NOP-expressing cells.	Buprenorphine	20-33	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	105-108	
26153065-8	2015	Chronic exposure to buprenorphine induced concentration-dependent AC superactivation in cells expressing KOP+NOP receptors, and the level of this superactivation was even higher in KOP+MOP+NOP-expressing cells.	Buprenorphine	20-33	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	181-184	
26153065-7	2015	Buprenorphine, when applied acutely, inhibited AC activity to ~90% in cells expressing KOP+MOP+NOP receptors.	Buprenorphine	0-13	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	87-90	
24761755-3	2014	In this study it is shown that a phenyl ring analogue (1d) of buprenorphine displays the desired profile in vitro with high, nonselective affinity for the MOP, KOP, and DOP receptors coupled with moderate affinity for NOP receptors.	Buprenorphine	62-75	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	160-163