PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24680675-3 2014 For this study we selected the murine 5HT2A/2C receptor agonist-induced head twitch response (HTR) induced by the administration of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), which has been proposed as an animal model of symptoms associated with a variety of behavioral and psychiatric conditions. 4-iodo-2,5-dimethoxyphenylisopropylamine 132-177 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 38-55 23353901-0 2013 Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model. 4-iodo-2,5-dimethoxyphenylisopropylamine 133-164 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 12-27 15705738-2 2005 WAY-163909 displaced [(125)I]2,5-dimethoxy-4-iodoamphetamine binding from human 5-HT(2C) receptor sites, in Chinese hamster ovary (CHO) cell membranes, with a K(i) value of 10.5 +/- 1.1 nM. 4-iodo-2,5-dimethoxyphenylisopropylamine 29-60 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 80-97 12486144-6 2002 In contrast, a 4 d treatment with the 5-HT2A/2C agonist (+/-)-1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane significantly increases the editing frequency at the C" site and leads to increased expression of 5-HT2C mRNA isoforms encoding receptors that activate G-protein least efficiently. 4-iodo-2,5-dimethoxyphenylisopropylamine 56-107 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 206-212 35449450-3 2022 Using the psychedelic 5-HT2A/5-HT2C receptor agonist 2,5-dimethoxy-4-iodoamphetamine (DOI) and 5-HT2A receptor knockout (KO) mice we investigated the effect of 5-HT2A receptor activation on emotional processing. 4-iodo-2,5-dimethoxyphenylisopropylamine 53-84 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 29-44