PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17416481-4	2007	ER stress inducers (tunicamycin, thapsigargin and oxidized dithiothreitol (DTTox)) resulted in a dose-dependent increase in GRP78 and GRP94 stress protein expression, but the magnitude of induction was cell line- and inducer-dependent.	dttox	75-80	heat shock protein family A (Hsp70) member 5	Sus scrofa	124-129	
9268305-6	1997	Furthermore, the ring-open intermolecular disulfide form of DTTox, 2-hydroxyethyl disulfide, was only a weak inducer of grp78 and gadd153 but was a strong inducer of hsp70 mRNA and a potent oxidant that lowered the NADPH/NADP+ ratio and depleted reduced glutathione (GSH).	dttox	60-65	heat shock protein family A (Hsp70) member 5	Sus scrofa	120-125	
9268304-6	1997	Prior heat shock did not protect cells from IDAM but pretreatment with trans-4,5-dihydroxy-1,2-dithiane (DTTox), thapsigargin, or tunicamycin enhanced expression of the endoplasmic reticulum (ER) chaperones GRP78 and GRP94 and rendered cells tolerant to IDAM.	dttox	105-110	heat shock protein family A (Hsp70) member 5	Sus scrofa	207-212	
9268305-1	1997	trans-4,5-Dihydroxy-1,2-dithiane, the intramolecular disulfide form of dithiothreitol (DTTox) transcriptionally activates the stress-responsive genes gadd153(chop) and grp78.	dttox	87-92	heat shock protein family A (Hsp70) member 5	Sus scrofa	168-173	
9268305-3	1997	DTTox activated both grp78 and gadd153 transcriptionally, but gadd153 mRNA stability also increased suggesting that both transcriptional and posttranscriptional mechanisms are involved.	dttox	0-5	heat shock protein family A (Hsp70) member 5	Sus scrofa	21-26	
9268305-8	1997	LLC-PK1 cells reduced DTTox to DTT, and the kinetics as well as the concentration dependence for reduction correlated with induction of both grp78 and gadd153 mRNA.	dttox	22-27	heat shock protein family A (Hsp70) member 5	Sus scrofa	141-146