PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11046127-5 2000 In poor metabolizer microsomes, either TAO or anti-CYP3A4 could alone abolish 5-OH-OP formation. 5-oh-op 78-85 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 51-57 12623762-12 2003 Both CYP2C19 and CYP3A contribute to the further elimination of 5-OH-OP and OP sulfone. 5-oh-op 64-71 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 17-22 11501187-7 2000 Both anti-CYP2C8/9/19 and anti-CYP3A4 had a significant inhibitory effect (P < 0.05) on the 5-OH-OP formation in a substrate concentration-dependent manner, and anti-CYP3A4 alone could almost abolish the formation of OPS (> 87%). 5-oh-op 95-102 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 31-37 11501187-7 2000 Both anti-CYP2C8/9/19 and anti-CYP3A4 had a significant inhibitory effect (P < 0.05) on the 5-OH-OP formation in a substrate concentration-dependent manner, and anti-CYP3A4 alone could almost abolish the formation of OPS (> 87%). 5-oh-op 95-102 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 169-175