PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18272928-2	2008	Loading granulosa cells with 22- or 25-hydroxycholesterol decreased NPC-1 mRNA, whereas culturing in cholesterol-depleted medium or inhibition of cholesterol biosynthesis increased NPC-1 promoter activity and NPC-1 mRNA abundance.	Hydroxycholesterols	39-57	NPC intracellular cholesterol transporter 1	Homo sapiens	68-73	
17989073-5	2008	Unexpectedly, we encountered NPC1 in a search for a membrane protein that binds 25-hydroxycholesterol (25-HC) and other oxysterols.	Hydroxycholesterols	83-101	NPC intracellular cholesterol transporter 1	Homo sapiens	29-33	
1543723-5	1992	In contrast, cholesterol esterification in NPD fibroblasts increased slowly during the first 6-12 h and reached 50% of normal values by 24 h. 25-Hydroxycholesterol, a non-lipoprotein stimulator of cholesterol esterification, caused a similar stimulation of cholesterol esterification in NPC, NPD and normal cells.	Hydroxycholesterols	145-163	NPC intracellular cholesterol transporter 1	Homo sapiens	287-290