PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17245169-15	2007	These lovastatin-induced changes in tPA and PAI-1 production were significantly reversed by the addition of MVA, GGPP, and FPP.	Mevalonic Acid	108-111	serpin family E member 1	Homo sapiens	44-49	
17046548-6	2006	The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor cerivastatin inhibited TNF-alpha-induced PAI-1 production by 59%, which was reversed by coincubation with mevalonic acid.	Mevalonic Acid	168-182	serpin family E member 1	Homo sapiens	103-108	
12659988-2	2003	Experimental studies have shown that lipoproteins or mevalonate regulate matrix metalloproteinase (MMP)-9, tissue factor (TF), plasminogen activator inhibitor-1 (PAI-1) expression, providing nonlipid mechanism.	Mevalonic Acid	53-63	serpin family E member 1	Homo sapiens	127-160	
12659988-2	2003	Experimental studies have shown that lipoproteins or mevalonate regulate matrix metalloproteinase (MMP)-9, tissue factor (TF), plasminogen activator inhibitor-1 (PAI-1) expression, providing nonlipid mechanism.	Mevalonic Acid	53-63	serpin family E member 1	Homo sapiens	162-167	
10928471-5	2000	Mevalonate (100 microM), a precursor of isoprenoids, added to cells simultaneously with fluvastatin, suppressed the effect of the drug on PAI-1 both in unstimulated and stimulated cells as well as on t-PA antigen.	Mevalonic Acid	0-10	serpin family E member 1	Homo sapiens	138-143	
12371961-9	2002	The effects of simvastatin were prevented in the presence of mevalonate and geranylgeraniol, suggesting that the effect of simvastatin on t-PA and PAI-1 synthesis is mediated through geranylgeranyl-modified intermediates.	Mevalonic Acid	61-71	serpin family E member 1	Homo sapiens	147-152	
23479762-6	2013	PAI-1 mRNA and protein expression levels were both increased with high glucose concentrations, but they were significantly suppressed by simvastatin and atorvastatin treatment (P < 0.01) and the effects were reversed by mevalonate (100 mumol/L) and geranylgeranyl pyrophosphate (10 mumol/L) but not farnesyl pyrophosphate (10 mumol/L).	Mevalonic Acid	223-233	serpin family E member 1	Homo sapiens	0-5