PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7669073-5	1995	The apparent Km values (at 100 microM acetyl CoA as co-substrate) of the different NAT2 variants for sulphamethazine, dapsone, p-anisidine, 2-aminofluorene, procainamide and isoniazid were determined.	2-aminofluorene	140-155	N-acetyltransferase 2	Homo sapiens	83-87	
28523442-2	2017	NAT2 also catalyzes the N-acetylation of aromatic amine carcinogens such as 2-aminofluorene and the O- and N,O-acetylation of aromatic amine and heterocyclic amine metabolites.	2-aminofluorene	76-91	N-acetyltransferase 2	Homo sapiens	0-4	
17936995-1	2007	The product of gene NAT2 (N-acetyltransferase 2) is involved in the biotransformation system and participates in detoxication of some arylamine derivatives (in particular 2-aminofluorene, 4-aminobiphenyl and 4-naphthylamine) which are strongly mutagenic and carcinogenic.	2-aminofluorene	171-186	N-acetyltransferase 2	Homo sapiens	20-24	
17936995-1	2007	The product of gene NAT2 (N-acetyltransferase 2) is involved in the biotransformation system and participates in detoxication of some arylamine derivatives (in particular 2-aminofluorene, 4-aminobiphenyl and 4-naphthylamine) which are strongly mutagenic and carcinogenic.	2-aminofluorene	171-186	N-acetyltransferase 2	Homo sapiens	26-47	
12618593-5	2003	A gene dose-response (NAT2*15/*15>NAT2*15/*16A>NAT2*16A/*16A) relationship was observed in liver and prostate cytosol towards the N-acetylation of p-aminobenzoic acid, 2-aminofluorene, beta-napthylamine, 4-aminobiphenyl, and 3,2"-dimethyl-4-aminobiphenyl.	2-aminofluorene	174-189	N-acetyltransferase 2	Homo sapiens	22-26	
12618593-5	2003	A gene dose-response (NAT2*15/*15>NAT2*15/*16A>NAT2*16A/*16A) relationship was observed in liver and prostate cytosol towards the N-acetylation of p-aminobenzoic acid, 2-aminofluorene, beta-napthylamine, 4-aminobiphenyl, and 3,2"-dimethyl-4-aminobiphenyl.	2-aminofluorene	174-189	N-acetyltransferase 2	Homo sapiens	37-41	
12618593-5	2003	A gene dose-response (NAT2*15/*15>NAT2*15/*16A>NAT2*16A/*16A) relationship was observed in liver and prostate cytosol towards the N-acetylation of p-aminobenzoic acid, 2-aminofluorene, beta-napthylamine, 4-aminobiphenyl, and 3,2"-dimethyl-4-aminobiphenyl.	2-aminofluorene	174-189	N-acetyltransferase 2	Homo sapiens	37-41	
12618593-7	2003	NAT1 and NAT2 in liver and prostate catalysed -acetylation of the arylamines above and O-acetylation of N-hydroxy derivatives of 2-aminofluorene, 4-aminobiphenyl and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.	2-aminofluorene	129-144	N-acetyltransferase 2	Homo sapiens	9-13	
12222688-7	2002	The enzymatic activities for N-acetylation of two arylamine carcinogens (2-aminofluorene, 4-aminobiphenyl), and a sulfonamide drug (sulfamethazine) were over 100-fold lower for NAT2 19 compared to reference NAT2 4.	2-aminofluorene	73-88	N-acetyltransferase 2	Homo sapiens	177-181	
12222688-7	2002	The enzymatic activities for N-acetylation of two arylamine carcinogens (2-aminofluorene, 4-aminobiphenyl), and a sulfonamide drug (sulfamethazine) were over 100-fold lower for NAT2 19 compared to reference NAT2 4.	2-aminofluorene	73-88	N-acetyltransferase 2	Homo sapiens	207-211	
11337936-5	2001	Reductions in catalytic activity for the N-acetylation of a sulfonamide drug (sulfamethazine) and an aromatic amine carcinogen (2-aminofluorene) were observed for NAT2 variants possessing G191A (R64Q), T341C (I114T), A434C (E145P), G590A (R197Q), A845C (K282T) or G857A (G286T).	2-aminofluorene	128-143	N-acetyltransferase 2	Homo sapiens	163-167	
9459121-4	1998	Forty-eight hours after irradiation of UVB (200 J/m2), the activity was not increased (114 +/- 8.3%, n = 3), while increase in N-acetylating capacity for 2-aminofluorene (substrate for NAT1 and NAT2) amounted to 201 +/- 16% (n = 3).	2-aminofluorene	154-169	N-acetyltransferase 2	Homo sapiens	194-198	
8425184-16	1993	In rapid acetylator hamster colon, NAT2/NAT1 activity ratios were 18 and 13 for the N-acetylation of 2-aminofluorene and 4-aminobiphenyl and 28 for the O-acetylation of N-hydroxy-2-aminofluorene.	2-aminofluorene	101-116	N-acetyltransferase 2	Homo sapiens	35-39	
1996083-10	1991	Interestingly, the carcinogen 2-aminofluorene was very efficiently metabolized by both NAT1 and NAT2.	2-aminofluorene	30-45	N-acetyltransferase 2	Homo sapiens	96-100