PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27002827-11 2017 Prior administration of cilostamide reversed the anorectic and body weight-reducing effects as well as stimulatory effect of insulin on hypothalamic Pomc mRNA levels. cilostamide 24-35 pro-opiomelanocortin-alpha Mus musculus 149-153 27002827-13 2017 CONCLUSION: Insulin induction of hypothalamic PDE3B activity and the reversal of the anorectic and body weight-reducing effects and stimulatory effect of insulin on hypothalamic Pomc gene expression by cilostamide suggest that activation of PDE3B is a novel mechanism of insulin signaling in the hypothalamus. cilostamide 202-213 pro-opiomelanocortin-alpha Mus musculus 178-182 22001576-4 2011 Recently, we have demonstrated that cilostamide reversed the leptin-induced increase in proopiomelanocortin (POMC) gene expression in the hypothalamus. cilostamide 36-47 pro-opiomelanocortin-alpha Mus musculus 88-107 22001576-4 2011 Recently, we have demonstrated that cilostamide reversed the leptin-induced increase in proopiomelanocortin (POMC) gene expression in the hypothalamus. cilostamide 36-47 pro-opiomelanocortin-alpha Mus musculus 109-113