PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6206325-1 1984 In 41 normotensive volunteers (diastolic pressure, less than 90 mm Hg) the beta 2-adrenoceptor density in lymphocytes was determined by (+/-)-125 iodocyanopindolol (ICYP) binding and compared with that in nine patients with borderline hypertension (diastolic pressure, 90-95 mm Hg) and 45 patients with established essential hypertension (diastolic pressure, greater than 95 mm Hg). Iodocyanopindolol 146-163 adrenoceptor beta 2 Homo sapiens 75-94 7977723-2 1994 We report here that membrane preparations of female rat thymic tissue contain iodocyanopindolol binding sites that exhibit pharmacological properties typical of a beta-AR. Iodocyanopindolol 78-95 adrenoceptor beta 2 Homo sapiens 163-170 6090853-1 1984 A saturable, stereospecific high affinity beta 2 adrenergic receptor was demonstrated on intact human peripheral blood lymphocytes using the ligand [125I]-iodocyanopindolol ([125I]ICYP). Iodocyanopindolol 155-172 adrenoceptor beta 2 Homo sapiens 42-68 12606629-5 2003 Saturation binding of [(125)I]iodocyanopindolol to beta-AR subtypes revealed the presence of a high-affinity site (K(d1) = 96.4 +/- 8.7 pM; B(max1) = 12.5 +/- 0.6 fmol/mg protein) and a low-affinity site (K(d2) = 1.96 +/- 1.7 nM; B(max2) = 58.7 +/- 4.3 fmol/mg protein). Iodocyanopindolol 30-47 adrenoceptor beta 2 Homo sapiens 51-58 12531948-6 2003 Beta(2) adrenoreceptor expression was assessed monthly using a ligand binding assay with [(125)I]iodocyanopindolol. Iodocyanopindolol 97-114 adrenoceptor beta 2 Homo sapiens 0-22 1328244-2 1992 At 48 h post-infection, a high level expression of an epitope-tagged beta 2-AR (10-25 pmol/mg protein) was detected by [125I]iodocyanopindolol ([125I]CYP) binding assays. Iodocyanopindolol 125-142 adrenoceptor beta 2 Homo sapiens 69-78 17418176-6 2007 The solubilised beta(2)-adrenergic receptor retained its binding affinity in a radio-receptor assay based on the competition for the binding to receptors between a ligand (beta-agonist or antagonist) and the radioligand [(125)I]iodocyanopindolol. Iodocyanopindolol 228-245 adrenoceptor beta 2 Homo sapiens 16-43