PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22761658-0 2012 Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha. triclocarban 0-12 estrogen receptor 1 Homo sapiens 124-147 24740835-4 2014 The tested concentrations of TCS and TCC were both from 1 x 10(-9) to 1 x 10(-6) M. Results showed that TCS and TCC exerted estrogenic activities by inducing luciferase activities in an ER reporter gene assay, promoting the proliferation of the MCF-7 cells, up-regulating the expression of pS2 and down-regulating ERalpha expression at both the mRNA and protein levels in the MCF-7 cells. triclocarban 37-40 estrogen receptor 1 Homo sapiens 315-322 24740835-4 2014 The tested concentrations of TCS and TCC were both from 1 x 10(-9) to 1 x 10(-6) M. Results showed that TCS and TCC exerted estrogenic activities by inducing luciferase activities in an ER reporter gene assay, promoting the proliferation of the MCF-7 cells, up-regulating the expression of pS2 and down-regulating ERalpha expression at both the mRNA and protein levels in the MCF-7 cells. triclocarban 113-116 estrogen receptor 1 Homo sapiens 315-322