PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31703116-7 2019 Importantly, ETX-induced BBB permeability requires expression of both MAL and caveolin-1, as mice deficient in MAL or caveolin-1 did not exhibit ETX-induced BBB permeability. 2-ethoxyethanol 13-16 caveolin 1, caveolae protein Mus musculus 78-88 31703116-7 2019 Importantly, ETX-induced BBB permeability requires expression of both MAL and caveolin-1, as mice deficient in MAL or caveolin-1 did not exhibit ETX-induced BBB permeability. 2-ethoxyethanol 13-16 caveolin 1, caveolae protein Mus musculus 118-128 31703116-10 2019 Based on these results, we hypothesize that ETX binds to MAL on the apical surface of brain endothelial cells, causing recruitment of caveolin-1, triggering caveolae formation and internalization. 2-ethoxyethanol 44-47 caveolin 1, caveolae protein Mus musculus 134-144