PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12974653-1 2003 Allenes with a nucleophilic functionality connected to the alpha-carbon atom have been shown to be versatile building blocks for the syn-thesis of gamma-butenolides, gamma-lactams, gamma-iminolactones, vinylic epoxides, 4-amino-2-alkenols, 2-amino-3-alkenols, 2,5-dihydrofurans, furans, vinylic cyclopropanes, and cyclopentenes, depending on the nature of the nucleophilic centers. 2-amino-3-alkenols 240-258 synemin Homo sapiens 133-136