PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30224059-0	2018	Ca2+-dependent inhibition of branched-chain alpha-ketoacid dehydrogenase kinase by thiamine pyrophosphate.	Thiamine Pyrophosphate	83-105	branched chain keto acid dehydrogenase kinase	Homo sapiens	29-79	
30224059-3	2018	The present study shows that free Ca2+ in the physiological range greatly increases the sensitivity of BDK to inhibition by TPP (IC50 of 2.5 muM in the presence of 1 muM free Ca2+).	Thiamine Pyrophosphate	124-127	branched chain keto acid dehydrogenase kinase	Homo sapiens	103-106	
30224059-2	2018	Thiamine pyrophosphate (TPP) is required as a coenzyme for the E1 component of the BCKDH complex and can also bring about activation of the complex by inhibiting BDK.	Thiamine Pyrophosphate	0-22	branched chain keto acid dehydrogenase kinase	Homo sapiens	162-165	
30224059-2	2018	Thiamine pyrophosphate (TPP) is required as a coenzyme for the E1 component of the BCKDH complex and can also bring about activation of the complex by inhibiting BDK.	Thiamine Pyrophosphate	24-27	branched chain keto acid dehydrogenase kinase	Homo sapiens	162-165	
19420697-0	2009	Inhibition of branched-chain alpha-ketoacid dehydrogenase kinase by thiamine pyrophosphate at different potassium ionic levels.	Thiamine Pyrophosphate	68-90	branched chain keto acid dehydrogenase kinase	Homo sapiens	14-64	
19420697-1	2009	Inhibition of branched-chain alpha-ketoacid dehydrogenase kinase (BDK) by thiamine pyrophosphate (TPP) was analyzed at two potassium ion (K(+)) concentrations.	Thiamine Pyrophosphate	74-96	branched chain keto acid dehydrogenase kinase	Homo sapiens	14-64	
19420697-1	2009	Inhibition of branched-chain alpha-ketoacid dehydrogenase kinase (BDK) by thiamine pyrophosphate (TPP) was analyzed at two potassium ion (K(+)) concentrations.	Thiamine Pyrophosphate	74-96	branched chain keto acid dehydrogenase kinase	Homo sapiens	66-69	
19420697-1	2009	Inhibition of branched-chain alpha-ketoacid dehydrogenase kinase (BDK) by thiamine pyrophosphate (TPP) was analyzed at two potassium ion (K(+)) concentrations.	Thiamine Pyrophosphate	98-101	branched chain keto acid dehydrogenase kinase	Homo sapiens	14-64	
19420697-1	2009	Inhibition of branched-chain alpha-ketoacid dehydrogenase kinase (BDK) by thiamine pyrophosphate (TPP) was analyzed at two potassium ion (K(+)) concentrations.	Thiamine Pyrophosphate	98-101	branched chain keto acid dehydrogenase kinase	Homo sapiens	66-69	
19420697-3	2009	These results suggest that BDK is less sensitive to TPP inhibition under physiological TPP and K(+) concentrations.	Thiamine Pyrophosphate	52-55	branched chain keto acid dehydrogenase kinase	Homo sapiens	27-30	
19420697-3	2009	These results suggest that BDK is less sensitive to TPP inhibition under physiological TPP and K(+) concentrations.	Thiamine Pyrophosphate	87-90	branched chain keto acid dehydrogenase kinase	Homo sapiens	27-30