PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17380453-0 2007 [Protein kinase B inhibitor enhance sensitivity of gastric cancer cell to etoposide]. Etoposide 74-83 protein tyrosine kinase 2 beta Homo sapiens 1-17 17380453-2 2007 To explore the relationship between PKB activity in gastric cancer cells and their sensitivity to etoposide chemotherapy. Etoposide 98-107 protein tyrosine kinase 2 beta Homo sapiens 36-39 17380453-4 2007 The PKB activities of these cell lines were detected by nonradioactive protein-kinase assay at different time points after etoposide treatment for 0,3,6,12,24 h with or without wortmannin pretreatment. Etoposide 123-132 protein tyrosine kinase 2 beta Homo sapiens 4-7 17380453-7 2007 Etoposide treatment resulted in increase in PKB activity and apoptosis rate,and decrease in cell survival rate in a time-dependent manner in gastric cancer cell lines. Etoposide 0-9 protein tyrosine kinase 2 beta Homo sapiens 44-47 17380453-9 2007 CONCLUSIONS: Etoposide can induce the PKB activity in gastric cancer cell lines. Etoposide 13-22 protein tyrosine kinase 2 beta Homo sapiens 38-41 17380453-1 2007 OBJECTIVE: To observe the effects of etoposide on protein kinase B (PKB) activity in distinct differentiated gastric cancer cell lines and the change of sensitivity to etoposide after pretreatment by wortmannin, a PKB inhibitor. Etoposide 37-46 protein tyrosine kinase 2 beta Homo sapiens 50-66 17380453-1 2007 OBJECTIVE: To observe the effects of etoposide on protein kinase B (PKB) activity in distinct differentiated gastric cancer cell lines and the change of sensitivity to etoposide after pretreatment by wortmannin, a PKB inhibitor. Etoposide 37-46 protein tyrosine kinase 2 beta Homo sapiens 68-71 17380453-1 2007 OBJECTIVE: To observe the effects of etoposide on protein kinase B (PKB) activity in distinct differentiated gastric cancer cell lines and the change of sensitivity to etoposide after pretreatment by wortmannin, a PKB inhibitor. Etoposide 168-177 protein tyrosine kinase 2 beta Homo sapiens 214-217 11914104-8 2002 Adhesion to ECM proteins stimulated protein tyrosine kinase (PTK) activity in both untreated and etoposide-treated cells. Etoposide 97-106 protein tyrosine kinase 2 beta Homo sapiens 61-64