PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16774472-6 2006 Systemic administration of the 3-hydroxyanthranilate-3,4-dioxygenase (3-HAD) inhibitor, 4-chloro-3-hydroxyanthranilate (4Cl-3HAA; approximately 100 mg/kg every 12 h, beginning 5 h after injury) attenuated local QUIN production and reduced QUIN accumulation at the site of injury by approximately 50% at day 12, without enhanced accumulations of the neuroprotective metabolite kynurenic acid (KYNA). Kynurenic Acid 376-390 3-hydroxyanthranilate 3,4-dioxygenase Cavia porcellus 31-68