PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3419426-2	1988	The dithiol 1,4-dithiothreitol (1,4-DTT) protected against and reversed the inhibition of glucokinase by alloxan.	Dithiothreitol	32-39	glucokinase	Homo sapiens	90-101	
3207996-15	1988	DTT (dithiothreitol) protected glucokinase against inhibition by alloxan and reversed the inhibition of the enzyme induced by alloxan.	Dithiothreitol	0-3	glucokinase	Homo sapiens	31-42	
3207996-15	1988	DTT (dithiothreitol) protected glucokinase against inhibition by alloxan and reversed the inhibition of the enzyme induced by alloxan.	Dithiothreitol	5-19	glucokinase	Homo sapiens	31-42	
3419426-9	1988	Glucose and 1,4-DTT protected glucokinase against this inhibition.	Dithiothreitol	12-19	glucokinase	Homo sapiens	30-41	
3419426-4	1988	Only 1,3-dimercaptopropane, 1,4-dimercaptobutane, 1,4-dithioerythritol, and 1,4-DTT, with intermediate spacing between the SH groups, reversed the inhibition of glucokinase induced by alloxan.	Dithiothreitol	76-83	glucokinase	Homo sapiens	161-172	
10700381-10	2000	d-Glucose and dithiotreitol provided protection against alloxan-induced inhibition of wild-type glucokinase and all catalytically active cysteine mutants.	Dithiothreitol	14-27	glucokinase	Homo sapiens	96-107	
20855893-5	2010	GCK inactivation and down-regulation were predominantly mediated by ethanol metabolism-generated peroxynitrite, which were suppressed by the peroxynitrite scavengers N(gamma)-monomethyl-L-arginine, uric acid, and deferoxamine but not by the S-nitrosylation inhibitor DTT, indicating that tyrosine nitration is the predominant modification associated with GCK down-regulation and inactivation rather than S-nitrosylation of cysteine.	Dithiothreitol	267-270	glucokinase	Homo sapiens	0-3	
9048894-7	1997	The inhibition of glucokinase enzyme activity was reversed by dithiothreitol with an EC50 value of 9 microM for alloxan and of 50 microM for ninhydrin.	Dithiothreitol	62-76	glucokinase	Homo sapiens	18-29