PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19225411-2 2009 Monoclonal antibody 1C2 is a commercial antibody to normal human TATA-binding protein that detects long stretches of glutamine residues. Glutamine 117-126 TATA-box binding protein Homo sapiens 65-85 20587494-0 2010 Spinocerebellar ataxia type 17 associated with an expansion of 42 glutamine residues in TATA-box binding protein gene. Glutamine 66-75 TATA-box binding protein Homo sapiens 88-112 11823535-10 2002 Transfection studies using Spi-1 mutant constructs showed that the TATA-binding protein binding and glutamine-rich domains of Spi-1 were important for IL-1beta induction, whereas LPS induction required the proline, glutamic acid, serine, and threonine-rich domain containing serine 148 as well as the TATA-binding protein and glutamine-rich domains. Glutamine 100-109 TATA-box binding protein Homo sapiens 301-321 11823535-10 2002 Transfection studies using Spi-1 mutant constructs showed that the TATA-binding protein binding and glutamine-rich domains of Spi-1 were important for IL-1beta induction, whereas LPS induction required the proline, glutamic acid, serine, and threonine-rich domain containing serine 148 as well as the TATA-binding protein and glutamine-rich domains. Glutamine 326-335 TATA-box binding protein Homo sapiens 67-87 11448935-4 2001 This abnormal expansion of glutamine tracts in TBP bears 47--55 repeats, whereas the normal repeat number ranges from 29 to 42. Glutamine 27-36 TATA-box binding protein Homo sapiens 47-50 12235815-3 2001 This abnormal expansion of glutamine tracts in TBP ranges 47 to 55 repeats, whereas the normal repeat number ranges from 29 to 42. Glutamine 27-36 TATA-box binding protein Homo sapiens 47-50 8886170-4 1996 We and others believe that the TATA-binding protein (TBP) is an important candidate to investigate in these diseases as it contains a highly polymorphic stretch of glutamine codons, which are close to the threshold length where the polyglutamine tracts start to be associated with disease. Glutamine 164-173 TATA-box binding protein Homo sapiens 31-51 10484774-2 1999 The mutant TBP with an expanded polyglutamine stretch (63 glutamines) was demonstrated to be expressed in lymphoblastoid cell lines at a level comparable with that of wild-type TBP. Glutamine 58-68 TATA-box binding protein Homo sapiens 11-14 8886170-4 1996 We and others believe that the TATA-binding protein (TBP) is an important candidate to investigate in these diseases as it contains a highly polymorphic stretch of glutamine codons, which are close to the threshold length where the polyglutamine tracts start to be associated with disease. Glutamine 164-173 TATA-box binding protein Homo sapiens 53-56 7698028-2 1995 We have used oligonucleotide primers flanking a polymorphic stretch of 38 glutamine codons in the 5" coding region of the TBP gene to genetically map this gene. Glutamine 74-83 TATA-box binding protein Homo sapiens 122-125 7959796-4 1994 We suggest that the common motif is represented by the long string of glutamine codons, which characterizes the amino-terminal segment of human TBP: in fact, other proteins involved in transcription, such as TAF II 110, Sp1, and some homeobox proteins, are known to contain glutamine-rich segments. Glutamine 70-79 TATA-box binding protein Homo sapiens 144-147 7959796-4 1994 We suggest that the common motif is represented by the long string of glutamine codons, which characterizes the amino-terminal segment of human TBP: in fact, other proteins involved in transcription, such as TAF II 110, Sp1, and some homeobox proteins, are known to contain glutamine-rich segments. Glutamine 274-283 TATA-box binding protein Homo sapiens 144-147 8503450-7 1993 Direct sequencing of 157 unrelated human alleles demonstrated the presence of 20 different alleles which resulted in 29-40 consecutive glutamines in the amino-terminal region of TBP. Glutamine 135-145 TATA-box binding protein Homo sapiens 178-181 8114696-0 1994 Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein. Glutamine 36-45 TATA-box binding protein Homo sapiens 86-110 8114696-1 1994 We have used protein-blotting and protein affinity chromatography to demonstrate that each of the two glutamine-rich activation domains of the human transcription factor Sp1 can bind specifically and directly to the C-terminal evolutionarily conserved domain of the human TATA box-binding protein (TBP). Glutamine 102-111 TATA-box binding protein Homo sapiens 272-296 8114696-1 1994 We have used protein-blotting and protein affinity chromatography to demonstrate that each of the two glutamine-rich activation domains of the human transcription factor Sp1 can bind specifically and directly to the C-terminal evolutionarily conserved domain of the human TATA box-binding protein (TBP). Glutamine 102-111 TATA-box binding protein Homo sapiens 298-301 8114696-5 1994 These results support the notion that TBP is a direct and important target of glutamine-rich transcriptional activators. Glutamine 78-87 TATA-box binding protein Homo sapiens 38-41 8388502-4 1993 Cellular transcription factor TBP contains three glutamine-glycine sites, at amino acids 12, 18, and 108. Glutamine 49-58 TATA-box binding protein Homo sapiens 30-33 8388502-7 1993 Further mutations around the glutamine-glycine site at position 18 suggest that determinants other than the glutamine-glycine bond in TBP are also required for 3CPro-induced cleavage. Glutamine 29-38 TATA-box binding protein Homo sapiens 134-137 8388502-8 1993 An alanine at position P4 and a proline at position P2, proximal to the scissile glutamine-glycine pair, appear to be important for 3CPro-mediated cleavage of TBP. Glutamine 81-90 TATA-box binding protein Homo sapiens 159-162 8225909-10 1993 This putative protein contains glutamine-enriched regions between AA residues 427 and 682 which show homologies to the corresponding glutamine-enriched regions of a variety of cellular genes like human transcriptional initiation factor (TFIID: TATA box factor). Glutamine 31-40 TATA-box binding protein Homo sapiens 244-259 8225909-10 1993 This putative protein contains glutamine-enriched regions between AA residues 427 and 682 which show homologies to the corresponding glutamine-enriched regions of a variety of cellular genes like human transcriptional initiation factor (TFIID: TATA box factor). Glutamine 133-142 TATA-box binding protein Homo sapiens 244-259