PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8657566-7	1996	Further, the transactivation domain of hXBP-1 encompasses a large C-terminal region of the protein, containing domains rich in glutamine, serine and threonine, and proline and glutamine residues, as shown in transient transfection experiments using hXBP-1-GAL4 fusion proteins and a reporter gene under the control of GAL4-binding sites.	Glutamine	127-136	X-box binding protein 1	Homo sapiens	39-45	
8657566-7	1996	Further, the transactivation domain of hXBP-1 encompasses a large C-terminal region of the protein, containing domains rich in glutamine, serine and threonine, and proline and glutamine residues, as shown in transient transfection experiments using hXBP-1-GAL4 fusion proteins and a reporter gene under the control of GAL4-binding sites.	Glutamine	176-185	X-box binding protein 1	Homo sapiens	39-45	
29206200-0	2017	l-Glutamine Attenuates Apoptosis Induced by Endoplasmic Reticulum Stress by Activating the IRE1alpha-XBP1 Axis in IPEC-J2: A Novel Mechanism of l-Glutamine in Promoting Intestinal Health.	Glutamine	0-11	X-box binding protein 1	Homo sapiens	101-105	
30305738-6	2018	Mechanistically, induction of XBP1 regulated the abundance of glutamine carriers and thus limited the influx of glutamine that is necessary to sustain mitochondrial respiration in T cells under glucose-deprived conditions.	Glutamine	62-71	X-box binding protein 1	Homo sapiens	30-34	
30305738-6	2018	Mechanistically, induction of XBP1 regulated the abundance of glutamine carriers and thus limited the influx of glutamine that is necessary to sustain mitochondrial respiration in T cells under glucose-deprived conditions.	Glutamine	112-121	X-box binding protein 1	Homo sapiens	30-34	
29930756-9	2018	Limiting the availability of glutamine significantly ameliorates the lipotoxic effects of palmitate, reduces CHOP and XBP1(s) induction and restores the expression levels of HER2 and HER3.	Glutamine	29-38	X-box binding protein 1	Homo sapiens	118-122	
29206200-6	2017	Finally, in the milieu of TUNI-induced ERS, l-glutamine was found to maintain a high level of GRP78, alleviate CHOP-mediated apoptosis and activate the inositol requiring enzyme 1alpha (IRE1alpha)-X-box binding protein 1 (XBP1) axis.	Glutamine	44-55	X-box binding protein 1	Homo sapiens	197-220	
29206200-6	2017	Finally, in the milieu of TUNI-induced ERS, l-glutamine was found to maintain a high level of GRP78, alleviate CHOP-mediated apoptosis and activate the inositol requiring enzyme 1alpha (IRE1alpha)-X-box binding protein 1 (XBP1) axis.	Glutamine	44-55	X-box binding protein 1	Homo sapiens	222-226	
29206200-7	2017	A specific inhibitor of the IRE1alpha-XBP1 axis reversed the protective effect of l-glutamine by blocking the expression of IRE1alpha/XBP1s.	Glutamine	82-93	X-box binding protein 1	Homo sapiens	38-42	
25339305-13	2014	Interestingly, in glucose-deprived conditions, glutamine induced apoptosis and necrosis, arrested autophagy, and triggered the unfolded protein response (UPR) though GRP78-IRE1alpha with two possible outcomes: (i) inhibition of cell growth by JNK activation in most cells and, (ii) promotion of cell growth by spliced XBP1 in the minority of cells.	Glutamine	47-56	X-box binding protein 1	Homo sapiens	318-322	
23277279-5	2013	In addition, the phosphorylation of XBP-1u by extracellular regulated protein kinases1/2 (ERK1/2) on Ser61 and Ser176 was found to be critical for the increased interaction between XBP-1u and FoxO1 upon glutamine starvation.	Glutamine	203-212	X-box binding protein 1	Homo sapiens	36-41