PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10022752-2 1998 Increasing concentration of Tris-HCl (Tris) and sodium phosphate (PO4) buffers differentially affected MDZ 1"-OH and MDZ 4-OH formation rates and had a different effect on MDZ metabolism mediated by microsomes containing CYP3A4 versus CYP3A4 and CYP3A5. po4 66-69 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 246-252