PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15214037-3 2004 A naked Sindbis RNA replicon vector (SINrep5) encoding the herpes simplex virus type 1 protein VP22 linked to E7 (SINrep5-VP22/E7) generated significant antitumor effects against TC-1 and TC-1 P3(A15), tumors with down-regulated MHC class I expression. tc-1 p3 188-195 naked Mus musculus 2-7 15214037-4 2004 Naked SINrep5 RNA without the insert or an E7 vaccine also produced antitumor effects against TC-1 P3(A15) but not TC-1. tc-1 p3 94-101 naked Mus musculus 0-5 15214037-6 2004 In vivo Ab depletion experiments revealed that NK cells were important for the antitumor effects of naked RNA vaccines against TC-1 P3(A15) and that the antitumor effects were perforin-dependent. tc-1 p3 127-134 naked Mus musculus 100-105