PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25826408-6 2015 In 3T3-L1 adipocytes, kaempferol and coumestrol exhibited anti-adipogenic effects via downregulation of PPARgamma, c/EBPalpha, SREBP-1, and FAS. kaempferol 22-32 peroxisome proliferator activated receptor gamma Mus musculus 104-113 22975504-7 2012 Finally, co-transfection assays using luciferase reporter gene and reverse transcription-polymerase chain reaction (RT-PCR) analysis using peroxisome proliferator-activated receptor-gamma (PPARgamma) target genes indicated that kaempferol significantly repressed rosiglitazone-induced PPARgamma transcriptional activity. kaempferol 228-238 peroxisome proliferator activated receptor gamma Mus musculus 139-187 22975504-7 2012 Finally, co-transfection assays using luciferase reporter gene and reverse transcription-polymerase chain reaction (RT-PCR) analysis using peroxisome proliferator-activated receptor-gamma (PPARgamma) target genes indicated that kaempferol significantly repressed rosiglitazone-induced PPARgamma transcriptional activity. kaempferol 228-238 peroxisome proliferator activated receptor gamma Mus musculus 189-198 22975504-7 2012 Finally, co-transfection assays using luciferase reporter gene and reverse transcription-polymerase chain reaction (RT-PCR) analysis using peroxisome proliferator-activated receptor-gamma (PPARgamma) target genes indicated that kaempferol significantly repressed rosiglitazone-induced PPARgamma transcriptional activity. kaempferol 228-238 peroxisome proliferator activated receptor gamma Mus musculus 285-294 22975504-8 2012 Overall, our data suggests that kaempferol, a major component of RPF, may be beneficial in obesity, by reducing adipogenesis and balancing lipid homeostasis partly through the down-regulation of PPARgamma. kaempferol 32-42 peroxisome proliferator activated receptor gamma Mus musculus 195-204 22108137-6 2012 Interestingly, the regulatory effects of kaempferol on RUNX2 and PPARgamma-mediated transcriptional activity were impaired in TAZ-null mouse embryonic fibroblasts but recovered by restoration of TAZ expression. kaempferol 41-51 peroxisome proliferator activated receptor gamma Mus musculus 65-74