PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16608704-8	2006	In this paper, our emphasis is on the two highly nonlinear inwardly rectifying potassium currents, (IK1) and (IK,r).	Potassium	79-88	IKAROS family zinc finger 1	Homo sapiens	100-103	
10377339-6	1999	Only rostral hair cells exhibited an inactivating potassium current (IA), whereas an inwardly rectifying potassium current (IK1) was identified only in caudal AP hair cells.	Potassium	105-114	IKAROS family zinc finger 1	Homo sapiens	124-127	
15276477-1	2004	OBJECTIVE: The cardiac inwardly rectifying potassium current IK1 and its molecular correlates Kir2.1 and Kir2.2 play an important role in cardiac repolarisation and in the pathogenesis of hereditary long-QT syndrome (LQTS-7).	Potassium	43-52	IKAROS family zinc finger 1	Homo sapiens	61-64	
2335026-4	1990	Our aim was twofold: 1) to study the single-channel characteristics of potassium channels in human atrial single cells, present under basal conditions (iK1 and iK(ATP] or when stimulated with 10(-5) M acetylcholine; and 2) to calculate the contribution of these three channel types to the total basal potassium conductance in human atrial cells, and to compare the results with data on guinea pig atrial cells under the same conditions.	Potassium	71-80	IKAROS family zinc finger 1	Homo sapiens	152-155	
2335026-10	1990	The basal potassium conductance (i.e., in the absence of any exogenous hormone or neurotransmitter) was mainly due to iK1 channels in both human and guinea pig cells, a finding that is in contrast with previous reports.	Potassium	10-19	IKAROS family zinc finger 1	Homo sapiens	118-121	
2557769-2	1989	Recordings of the outward current(s), which is responsible for the resting potential and early repolarization of the action potential in human right atrium, consistently showed that this tissue has 1) a relatively small inwardly rectifying background potassium current (IK1) which generates the resting potential in mammalian ventricular tissue and Purkinje fibers, and 2) a large time- and voltage-dependent, but Ca2(+)-independent, transient outward current.	Potassium	251-260	IKAROS family zinc finger 1	Homo sapiens	270-273	
35548367-3	2022	Although changes in inward rectifier potassium currents including I K1 are known to contribute to the pathogenesis of fibrillation, the effect of sildenafil on I K1 has not been studied.	Potassium	37-46	IKAROS family zinc finger 1	Homo sapiens	66-70	
31868992-4	2020	One of the main challenges of hiPSC-CMs is the physiologic expression of ion channels such as the inward rectifiers (e.g., Kir2.1-2.3), which conduct the cardiac inward rectifier potassium current (IK1 ).	Potassium	179-188	IKAROS family zinc finger 1	Homo sapiens	198-201	
558594-8	1977	Alteration in potassium driving force over time results in a time-dependent ik1 even though the underlying conductance is time-independent [29].	Potassium	14-23	IKAROS family zinc finger 1	Homo sapiens	76-79	
33229908-3	2021	Various approaches are used to overcome this drawback, including the injection of a "synthetic" inward rectifier potassium current (IK1), which is computed in real time, based on the recorded membrane potential ("dynamic clamp").	Potassium	113-122	IKAROS family zinc finger 1	Homo sapiens	132-135	
31827438-2	2019	We explored if blocking the background and the acetylcholine-activated inward rectifier potassium currents (IK1 and IKACh) could be antiarrhythmic in persistent atrial fibrillation.	Potassium	88-97	IKAROS family zinc finger 1	Homo sapiens	108-111	
31946747-2	2019	Previous experimental studies have shown that biological pacemaker could be produced by genetically manipulating non-pacemaking cardiac cells by suppressing the inward rectifier potassium current (IK1) and expressing the hyperpolarization- activated current (If).	Potassium	178-187	IKAROS family zinc finger 1	Homo sapiens	197-200	
29245016-12	2018	Finally, electrophysiological studies showed that the inwardly rectifying potassium current (IK1) was evenly present in AF- and Ctr-CMPC in basal conditions and similarly disappeared after TGF-beta1 exposure.	Potassium	74-83	IKAROS family zinc finger 1	Homo sapiens	93-96	
30835490-6	2019	We reproduced key electrophysiological and pharmacological features known for native IK1, including current enhancement by external potassium and voltage- and concentration-dependent blockade by external barium.	Potassium	132-141	IKAROS family zinc finger 1	Homo sapiens	85-88	
27895596-1	2016	The inwardly rectifying potassium current (IK1) and the fast inward sodium current (INa) are reciprocally modulated in mammalian ventricular myocytes.	Potassium	24-33	IKAROS family zinc finger 1	Homo sapiens	43-46	
27895596-12	2016	Reciprocal modulation of the inwardly rectifying potassium current and the fast inward sodium current may have a functional role in allowing cardiac tissue to remain excitable when IK1 is upregulated.	Potassium	49-58	IKAROS family zinc finger 1	Homo sapiens	181-184	
26057242-4	2015	Our goal is to determine if the inward rectifying potassium current (IK1) causes the inhibition of hyperpolarization.	Potassium	50-59	IKAROS family zinc finger 1	Homo sapiens	69-72