PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29802687-1	2018	A number of aza-heterocyclic compounds, which share the 5,6-dihydropyrrolo[2,1-a]isoquinoline (DHPIQ) scaffold with members of the lamellarin alkaloid family, were synthesized and evaluated for their ability to reverse in vitro multidrug resistance in cancer cells through inhibition of P-glycoprotein (P-gp) and/or multidrug-resistance-associated protein 1.	Azathioprine	12-15	ATP binding cassette subfamily B member 1	Homo sapiens	287-301	
29802687-1	2018	A number of aza-heterocyclic compounds, which share the 5,6-dihydropyrrolo[2,1-a]isoquinoline (DHPIQ) scaffold with members of the lamellarin alkaloid family, were synthesized and evaluated for their ability to reverse in vitro multidrug resistance in cancer cells through inhibition of P-glycoprotein (P-gp) and/or multidrug-resistance-associated protein 1.	Azathioprine	12-15	ATP binding cassette subfamily B member 1	Homo sapiens	303-307	
17262810-0	2007	MDR1 polymorphisms and response to azathioprine therapy in patients with Crohn"s disease.	Azathioprine	35-47	ATP binding cassette subfamily B member 1	Homo sapiens	0-4	
20510207-5	2010	Moreover, increased transcription activity of c-Jun by the JNK activation contributed to the down-regulation of MDR1, thus indicating a central role of JNK signalling to suppress P-gp level in 5-Aza-treated Caki-1 cells.	Azathioprine	195-198	ATP binding cassette subfamily B member 1	Homo sapiens	112-116	
20510207-5	2010	Moreover, increased transcription activity of c-Jun by the JNK activation contributed to the down-regulation of MDR1, thus indicating a central role of JNK signalling to suppress P-gp level in 5-Aza-treated Caki-1 cells.	Azathioprine	195-198	ATP binding cassette subfamily B member 1	Homo sapiens	179-183	
24918007-8	2014	TT carriers of ABCB1 C3435T SNP had a higher chance of responding to azathioprine (OR 2.38, p = 0.01), while carriers of ABCB1 G2677T/A SNP, as well as responding better to azathioprine (OR 1.89, p = 0.07), had a lower chance of responding to biologicals (OR 0.31, p = 0.07), which became significant after adjusting for gender (OR 0.75, p = 0.005).	Azathioprine	69-81	ATP binding cassette subfamily B member 1	Homo sapiens	15-20	
24918007-8	2014	TT carriers of ABCB1 C3435T SNP had a higher chance of responding to azathioprine (OR 2.38, p = 0.01), while carriers of ABCB1 G2677T/A SNP, as well as responding better to azathioprine (OR 1.89, p = 0.07), had a lower chance of responding to biologicals (OR 0.31, p = 0.07), which became significant after adjusting for gender (OR 0.75, p = 0.005).	Azathioprine	173-185	ATP binding cassette subfamily B member 1	Homo sapiens	15-20	
17262810-1	2007	BACKGROUND: To investigate the contribution of multidrug resistance 1 (MDR1) gene pharmacogenetics (G2677T/A and C3435T) to the efficacy of azathioprine in inducing remission in patients with Crohn"s disease (CD).	Azathioprine	140-152	ATP binding cassette subfamily B member 1	Homo sapiens	47-69	
17262810-1	2007	BACKGROUND: To investigate the contribution of multidrug resistance 1 (MDR1) gene pharmacogenetics (G2677T/A and C3435T) to the efficacy of azathioprine in inducing remission in patients with Crohn"s disease (CD).	Azathioprine	140-152	ATP binding cassette subfamily B member 1	Homo sapiens	71-75	
1674429-3	1991	By applying the method of immunocytochemical assay, we have demonstrated the appearance of the multidrug-resistant phenotype (P-glycoprotein+ cells, multidrug-resistant cells) in mononuclear cells of the peripheral blood from 32/49 patients receiving triple-drug (azathioprine, steroids, cyclosporine) immunosuppressive therapy after heart transplantation.	Azathioprine	264-276	ATP binding cassette subfamily B member 1	Homo sapiens	126-140