PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12763054-3	2003	CYP3A4 and CYP4F2 were suggested to be involved in tocopherol degradation.	Tocopherols	51-61	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	11-17	
34785321-3	2022	Research has established that tocopherols and tocotrienols are metabolized via omega-hydroxylase (CYP4F2)-initiated side chain oxidation to form 13"-hydroxychromanol and 13"-carobyxychromanol (13"-COOH).	Tocopherols	30-41	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	98-104	
20861217-1	2010	Human cytochrome P450 4F2 (CYP4F2) catalyzes the omega-hydroxylation of the side chain of tocopherols (TOH) and tocotrienols (T3), the first step in their catabolism to polar metabolites excreted in urine.	Tocopherols	90-101	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	6-25	
20861217-1	2010	Human cytochrome P450 4F2 (CYP4F2) catalyzes the omega-hydroxylation of the side chain of tocopherols (TOH) and tocotrienols (T3), the first step in their catabolism to polar metabolites excreted in urine.	Tocopherols	90-101	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	27-33	
20861217-1	2010	Human cytochrome P450 4F2 (CYP4F2) catalyzes the omega-hydroxylation of the side chain of tocopherols (TOH) and tocotrienols (T3), the first step in their catabolism to polar metabolites excreted in urine.	Tocopherols	103-106	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	6-25	
20861217-1	2010	Human cytochrome P450 4F2 (CYP4F2) catalyzes the omega-hydroxylation of the side chain of tocopherols (TOH) and tocotrienols (T3), the first step in their catabolism to polar metabolites excreted in urine.	Tocopherols	103-106	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	27-33	
17284776-1	2007	Human cytochrome P450 4F2 (CYP4F2) catalyzes the initial omega-hydroxylation reaction in the metabolism of tocopherols and tocotrienols to carboxychromanols and is, to date, the only enzyme shown to metabolize vitamin E.	Tocopherols	107-118	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	6-25	
17284776-1	2007	Human cytochrome P450 4F2 (CYP4F2) catalyzes the initial omega-hydroxylation reaction in the metabolism of tocopherols and tocotrienols to carboxychromanols and is, to date, the only enzyme shown to metabolize vitamin E.	Tocopherols	107-118	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	27-33	
17284776-11	2007	These results indicate that CYP4F2-mediated tocopherol-omega-hydroxylation is a central feature underlying the different biological half-lives, and therefore biopotencies, of the tocopherols and tocotrienols.	Tocopherols	44-54	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	28-34	
17284776-11	2007	These results indicate that CYP4F2-mediated tocopherol-omega-hydroxylation is a central feature underlying the different biological half-lives, and therefore biopotencies, of the tocopherols and tocotrienols.	Tocopherols	179-190	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	28-34	
15753130-10	2004	Liver microsomes and recombinant CYP4F2 both exhibited substrate preference for gamma-TOH over alpha-TOH, and recent studies show that tocotrienols are catabolized more extensively than the corresponding tocopherols.	Tocopherols	204-215	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	33-39