PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15759029-1	2005	A lysosomal pathway, characterized by partial rupture of lysosomal membranes and cathepsin B activation, is activated during camptothecin (CPT)-induced apoptosis in U937 and Namalwa cancer cells.	Camptothecin	125-137	cathepsin B	Homo sapiens	81-92	
27070848-0	2016	Design, Synthesis, and Biological Evaluation of New Cathepsin B-Sensitive Camptothecin Nanoparticles Equipped with a Novel Multifuctional Linker.	Camptothecin	74-86	cathepsin B	Homo sapiens	52-63	
16874058-3	2006	(1) Camptothecin (CPT)-induced apoptosis in breast cancer MCF-7 cells is associated with activation of cathepsin B and aggregation of BAX and BID on mitochondria.	Camptothecin	4-16	cathepsin B	Homo sapiens	103-114	
16874058-3	2006	(1) Camptothecin (CPT)-induced apoptosis in breast cancer MCF-7 cells is associated with activation of cathepsin B and aggregation of BAX and BID on mitochondria.	Camptothecin	18-21	cathepsin B	Homo sapiens	103-114	
28033467-4	2017	The designed MOF probe can realize cathepsin B-activated cancer cell imaging and chemo-photodynamic dual-therapy combining Ce6 as the photosensitizer and the camptothecine drug.	Camptothecin	158-171	cathepsin B	Homo sapiens	35-46	
17378599-0	2007	Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy.	Camptothecin	28-40	cathepsin B	Homo sapiens	108-119	
17378599-4	2007	In the present work, we developed water-soluble camptothecin (CPT) and doxorubicin (DOXO) prodrugs that incorporate the peptide linker Ala-Leu-Ala-Leu that serves as a substrate for the tumor-associated protease, cathepsin B, which is overexpressed in several solid tumors.	Camptothecin	48-60	cathepsin B	Homo sapiens	213-224	
17378599-4	2007	In the present work, we developed water-soluble camptothecin (CPT) and doxorubicin (DOXO) prodrugs that incorporate the peptide linker Ala-Leu-Ala-Leu that serves as a substrate for the tumor-associated protease, cathepsin B, which is overexpressed in several solid tumors.	Camptothecin	62-65	cathepsin B	Homo sapiens	213-224	
16077201-2	2005	This study focused on the role of cathepsin B and its substrate, BID as molecular links between apoptosis and autophagy in human breast cancer MCF-7 cells exposed to camptothecin.	Camptothecin	166-178	cathepsin B	Homo sapiens	34-45	
15759029-1	2005	A lysosomal pathway, characterized by partial rupture of lysosomal membranes and cathepsin B activation, is activated during camptothecin (CPT)-induced apoptosis in U937 and Namalwa cancer cells.	Camptothecin	139-142	cathepsin B	Homo sapiens	81-92	
11755358-1	2002	The first immunoconjugate of camptothecin has been synthesized wherein the drug is attached to the tumor-recognizing antibody BR96 via a Cathepsin B cleavable linker.	Camptothecin	29-41	cathepsin B	Homo sapiens	137-148