PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25461556-0	2014	Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs.	Camptothecin	0-12	TNF receptor superfamily member 10b	Homo sapiens	97-113	
25200008-5	2014	Using the HCT116 colorectal cancer model, we show that following binding to DR5, the nanoparticles activate caspase 8, enhancing the anti-tumor activity of the camptothecin payload both in vitro and in vivo.	Camptothecin	160-172	TNF receptor superfamily member 10b	Homo sapiens	76-79	
25200008-6	2014	Importantly, the combination of nanoparticle-induced DR5 clustering with camptothecin delivery overcomes resistance to DR5-induced apoptosis caused by loss of BAX or overexpression of anti-apoptotic FLIP.	Camptothecin	73-85	TNF receptor superfamily member 10b	Homo sapiens	119-122	
14500373-4	2003	The chemotherapeutic drugs (paclitaxel, vincristine, vinblastine, etoposide, camptothecin, and Adriamycin) induced death receptors (DRs) TRAIL receptor 1/DR4 and TRAIL receptor 2/DR5, and successive treatment with TRAIL resulted in apoptosis of both TRAIL-sensitive and -resistant cells.	Camptothecin	77-89	TNF receptor superfamily member 10b	Homo sapiens	179-182	
21927023-4	2012	In this report, we demonstrate that ATF3 is required for efficient DR5 induction upon DNA damage by camptothecin (CPT) in colorectal cancer cells.	Camptothecin	100-112	TNF receptor superfamily member 10b	Homo sapiens	67-70	
21927023-4	2012	In this report, we demonstrate that ATF3 is required for efficient DR5 induction upon DNA damage by camptothecin (CPT) in colorectal cancer cells.	Camptothecin	114-117	TNF receptor superfamily member 10b	Homo sapiens	67-70	
21875750-6	2011	We also demonstrate that DR5-targeted nanoparticles encapsulating the cytotoxic drug camptothecin are effectively targeted to the tumour cells, thereby producing enhanced cytotoxic effects through simultaneous drug delivery and apoptosis induction.	Camptothecin	85-97	TNF receptor superfamily member 10b	Homo sapiens	25-28	
12610517-6	2003	We show that genotoxic agents such as cisplatin, doxorubicin and camptothecin, in addition to UV radiation, can induce TRAIL-R2 on the cell surface of TRAIL receptor-negative tumour cells.	Camptothecin	65-77	TNF receptor superfamily member 10b	Homo sapiens	119-127