PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25520194-6	2015	We show that RECQL5, but not BLM, conferred resistance to mitomycin C (MMC, an interstrand crosslinker) and camptothecin (CPT, a type 1 topoisomerase inhibitor) in FANCB-defective cells.	Camptothecin	108-120	RecQ like helicase 5	Homo sapiens	13-19	
26959889-2	2016	The five human RecQ helicases, RECQL1, Bloom, WRN, RECQL4 and RECQL5 play critical roles in DNA repair and cell survival after treatment with the anticancer drug camptothecin (CPT).	Camptothecin	162-174	RecQ like helicase 5	Homo sapiens	62-68	
26959889-2	2016	The five human RecQ helicases, RECQL1, Bloom, WRN, RECQL4 and RECQL5 play critical roles in DNA repair and cell survival after treatment with the anticancer drug camptothecin (CPT).	Camptothecin	176-179	RecQ like helicase 5	Homo sapiens	62-68	
21278449-5	2011	In particular, current studies have revealed the presence of a novel Recql5/RECQL5-dependent mechanism for suppressing replication fork collapse in response to global replication fork stalling following exposure to camptothecin (CPT), a topoisomerase I inhibitor, and a potent inhibitor of DNA replication.	Camptothecin	215-227	RecQ like helicase 5	Homo sapiens	69-75	
21278449-5	2011	In particular, current studies have revealed the presence of a novel Recql5/RECQL5-dependent mechanism for suppressing replication fork collapse in response to global replication fork stalling following exposure to camptothecin (CPT), a topoisomerase I inhibitor, and a potent inhibitor of DNA replication.	Camptothecin	215-227	RecQ like helicase 5	Homo sapiens	76-82	
21278449-5	2011	In particular, current studies have revealed the presence of a novel Recql5/RECQL5-dependent mechanism for suppressing replication fork collapse in response to global replication fork stalling following exposure to camptothecin (CPT), a topoisomerase I inhibitor, and a potent inhibitor of DNA replication.	Camptothecin	229-232	RecQ like helicase 5	Homo sapiens	69-75	
21278449-5	2011	In particular, current studies have revealed the presence of a novel Recql5/RECQL5-dependent mechanism for suppressing replication fork collapse in response to global replication fork stalling following exposure to camptothecin (CPT), a topoisomerase I inhibitor, and a potent inhibitor of DNA replication.	Camptothecin	229-232	RecQ like helicase 5	Homo sapiens	76-82	
20231364-5	2010	Fully functional RecQL5 requires both helicase activity and associations with the initiation polymerase, because mutants lacking either activity are partially defective in the suppression of sister chromatid exchange and resistance to camptothecin-induced DNA damage, and mutants lacking both activities are completely defective.	Camptothecin	235-247	RecQ like helicase 5	Homo sapiens	17-23	
22645136-3	2012	Here, we identified a BRC repeat variant, named BRCv, in the RECQL5 helicase, which possesses anti-recombinase activity in vitro and suppresses HR and promotes cellular resistance to camptothecin-induced replication stress in vivo.	Camptothecin	183-195	RecQ like helicase 5	Homo sapiens	61-67	
22645136-5	2012	Mutations of either motif compromised functions of RECQL5, including association with RAD51, inhibition of RAD51-mediated D-loop formation, suppression of sister chromatid exchange, and resistance to camptothecin-induced replication stress.	Camptothecin	200-212	RecQ like helicase 5	Homo sapiens	51-57	
21210765-0	2011	RECQL5 is an important determinant for camptothecin tolerance in human colorectal cancer cells.	Camptothecin	39-51	RecQ like helicase 5	Homo sapiens	0-6