PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9268358-8	1997	SPS19 is dispensable for growth and sporulation on solid acetate and oleate media, but is essential for these processes to occur on petroselineate.	Oleic Acid	69-75	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	0-5	
19583587-1	2009	The sporulation-specific gene SPS18 shares a common promoter region with the oleic acid-inducible gene SPS19.	Oleic Acid	77-87	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	103-108	
11170837-0	2000	Adr1p-dependent regulation of the oleic acid-inducible yeast gene SPS19 encoding the peroxisomal beta-oxidation auxiliary enzyme 2,4-dienoyl-CoA reductase.	Oleic Acid	34-44	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	66-71	
9268358-3	1997	The Saccharomyces cerevisiae Sps19p is 34% similar to the human and rat mitochondrial reductases, and an SPS19 deleted strain was unable to utilize petroselineate (cis-C18:1(6)) as the sole carbon source, but remained viable on oleate (cis-C18:1(9)).	Oleic Acid	228-234	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	105-110	
19583587-3	2009	Here, SPS19 oleate-response element (ORE) conferred activation on a basal CYC1-lacZ reporter gene equally in both orientations, but promoter analysis using SPS18-lacZ reporter constructs with deletions identified a repressing fragment containing a midsporulation element (MSE) that could be involved in imposing directionality towards SPS19 in oleic acid-induced cells.	Oleic Acid	344-354	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	6-11	
19583587-6	2009	We conclude that SPS18 MSE is a functional element repressing the expression of both SPS18 and SPS19, and is a component of a stricture mechanism shielding SPS18 from the dramatic increase in ORE-dependent transcription of SPS19 in oleic acid-grown cells.	Oleic Acid	232-242	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	95-100	
19583587-6	2009	We conclude that SPS18 MSE is a functional element repressing the expression of both SPS18 and SPS19, and is a component of a stricture mechanism shielding SPS18 from the dramatic increase in ORE-dependent transcription of SPS19 in oleic acid-grown cells.	Oleic Acid	232-242	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	223-228	
12748191-5	2003	Transcription of the oleic acid-inducible genes SPS19 and CTA1, which rely on both Pip2p-Oaf1p and Adr1p for their regulation, was reduced in adr1delta mutant cells.	Oleic Acid	21-31	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	48-53	
10589836-0	1999	A novel element in the promoter of the Saccharomyces cerevisiae gene SPS19 enhances ORE-dependent up-regulation in oleic acid and is essential for de-repression.	Oleic Acid	115-125	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	69-74	
10589836-3	1999	In a reporter construct containing a deletion adjacent to the ORE, transcriptional activation of SPS19 in oleic acid medium was impaired.	Oleic Acid	106-116	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	97-102	
10589836-6	1999	In oleic acid-containing medium, UAS(SPS19) stimulated transcription of the reporter gene 2.4-fold compared to the intact SPS19 ORE, but did so only in the presence of Pip2p and Oaf1p.	Oleic Acid	3-13	2,4-dienoyl-CoA reductase (NADPH)	Saccharomyces cerevisiae S288C	37-42