PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12748191-6 2003 However, by ectopically restoring levels of Pip2p in adr1delta cells grown on oleic acid medium, transcription of both genes increased 2-fold compared with the control. Oleic Acid 78-88 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 44-49 19583587-5 2009 Quantitative real-time PCR demonstrated that in haploid sum1Delta, hst1Delta, or rfm1Delta cells, oleic acid-dependent expression of SPS18 was higher compared with the situation in wild-type cells, but in the sum1Delta mutant, this effect was diminished in the absence of Oaf1p or Pip2p. Oleic Acid 98-108 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 281-286 16636289-6 2006 We demonstrate that the induction of Oaf1/Pip2 activity by the fatty acid oleate depends on oleate"s direct binding to the Oaf1 LBD. Oleic Acid 74-80 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 42-46 16636289-6 2006 We demonstrate that the induction of Oaf1/Pip2 activity by the fatty acid oleate depends on oleate"s direct binding to the Oaf1 LBD. Oleic Acid 92-98 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 42-46 12748191-0 2003 Saccharomyces cerevisiae PIP2 mediating oleic acid induction and peroxisome proliferation is regulated by Adr1p and Pip2p-Oaf1p. Oleic Acid 40-50 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 25-29 12748191-3 2003 Immunoprecipitation showed that, in adr1delta mutant cells grown on oleic acid, Pip2p was less abundant compared with the corresponding wild-type. Oleic Acid 68-78 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 80-85 12748191-5 2003 Transcription of the oleic acid-inducible genes SPS19 and CTA1, which rely on both Pip2p-Oaf1p and Adr1p for their regulation, was reduced in adr1delta mutant cells. Oleic Acid 21-31 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 83-88 18621837-6 2008 Simulations of the model suggest that 1), the intrinsic Adr1p-driven feed-forward loop reduces the steady-state expression variability of target genes; 2), the parallel Oaf3p-driven inhibitory feed-forward loop modulates the dynamic response of target genes to a transiently varying oleate concentration; and 3), heterodimerization of Oaf1p and Pip2p does not appear to have a noise-reducing function in the context of oleate-dependent expression of target genes. Oleic Acid 283-289 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 345-350 18621837-6 2008 Simulations of the model suggest that 1), the intrinsic Adr1p-driven feed-forward loop reduces the steady-state expression variability of target genes; 2), the parallel Oaf3p-driven inhibitory feed-forward loop modulates the dynamic response of target genes to a transiently varying oleate concentration; and 3), heterodimerization of Oaf1p and Pip2p does not appear to have a noise-reducing function in the context of oleate-dependent expression of target genes. Oleic Acid 419-425 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 345-350 9774671-1 1998 Two transcription factors, Oaf1p and Pip2p (Oaf2p), are key components in the pathway by which several Saccharomyces cerevisiae genes encoding peroxisomal proteins are activated in the presence of a fatty acid such as oleate. Oleic Acid 218-224 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 37-42 10589836-1 1999 In Saccharomyces cerevisiae cells grown on oleic acid, genes encoding enzymes of beta-oxidation are induced by the interaction of a transcription factor composed of Pip2p and Oaflp with an oleate response element (ORE) in their promoters. Oleic Acid 43-53 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 165-170 9813046-3 1998 Levels of ECI1 transcript were elevated in cells grown on oleic acid medium due to the presence in the ECI1 promoter of an oleate response element that bound the transcription factors Pip2p and Oaf1p. Oleic Acid 58-68 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 184-189 9774671-1 1998 Two transcription factors, Oaf1p and Pip2p (Oaf2p), are key components in the pathway by which several Saccharomyces cerevisiae genes encoding peroxisomal proteins are activated in the presence of a fatty acid such as oleate. Oleic Acid 218-224 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 44-49 8670793-7 1996 A pip2 deletion strain is impaired in growth on oleate as sole carbon source and the induction of beta-oxidation enzymes is abolished. Oleic Acid 48-54 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 2-6