PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8772510-5 1996 Infusing oleic acid into unadapted rats stimulated CCK secretion and pancreatic exocrine secretion to levels observed with triglycerides in adapted rats. Oleic Acid 9-19 cholecystokinin Rattus norvegicus 51-54 11557510-7 2001 In summary, long- and short-chain fatty acids activate intestinal vagal afferents by different mechanisms; oleate acts via a CCK-mediated mechanism and butyrate appears to have a direct effect on afferent terminals. Oleic Acid 107-113 cholecystokinin Rattus norvegicus 125-128 9138250-0 1997 Involvement of cholinergic processes in cholecystokinin (CCK) release [corrected] by luminal oleic acid. Oleic Acid 93-103 cholecystokinin Rattus norvegicus 40-55 9138250-0 1997 Involvement of cholinergic processes in cholecystokinin (CCK) release [corrected] by luminal oleic acid. Oleic Acid 93-103 cholecystokinin Rattus norvegicus 57-60 7537680-6 1995 Endogenous CCK released by intraduodenal instillation of oleate prevented the formation of acute gastric lesions induced by both ethanol and aspirin and the protective effects were abolished by pretreatment with loxiglumide. Oleic Acid 57-63 cholecystokinin Rattus norvegicus 11-14 8594945-0 1995 Role of cholecystokinin in the anorexia produced by duodenal delivery of oleic acid in rats. Oleic Acid 73-83 cholecystokinin Rattus norvegicus 8-23 8594945-7 1995 Our results suggest that the satiety response to triolein is produced by the products of triolein digestion and that CCK plays a significant, indispensable role in mediating the satiety response to duodenal delivery of small but not large loads of oleic acid. Oleic Acid 248-258 cholecystokinin Rattus norvegicus 117-120 7481522-4 1995 CCK released by duodenal oleate also protected gastric mucosa against this damage. Oleic Acid 25-31 cholecystokinin Rattus norvegicus 0-3 8125532-6 1993 CR1505, a CCK-receptor antagonist, significantly attenuated the oleic acid-induced increase in IgA secretion into the intestinal lumen, but did not affect the oleic acid-induced decrease in lymphatic IgA secretion. Oleic Acid 64-74 cholecystokinin Rattus norvegicus 10-13 8498606-6 1993 Previously we demonstrated that CCK receptor antagonists attenuate suppression of sham feeding by intestinal infusion of either oleate or maltose, suggesting that endogenous CCK participates in suppression of sham feeding by some intestinal nutrients. Oleic Acid 128-134 cholecystokinin Rattus norvegicus 32-35 8498606-6 1993 Previously we demonstrated that CCK receptor antagonists attenuate suppression of sham feeding by intestinal infusion of either oleate or maltose, suggesting that endogenous CCK participates in suppression of sham feeding by some intestinal nutrients. Oleic Acid 128-134 cholecystokinin Rattus norvegicus 174-177 8464169-0 1993 [Plasma cholecystokinin levels in rats with pancreatic insufficiency induced by intra ductal injection of oleic acid]. Oleic Acid 106-116 cholecystokinin Rattus norvegicus 8-23 8464169-4 1993 Plasma CCK bioactivity was significantly increased from the pre-treatment values of 0.8 +/- 0.1pM to 5.1 +/- 1.4pM at 24h after oleic acid treatment. Oleic Acid 128-138 cholecystokinin Rattus norvegicus 7-10 8464169-6 1993 Even after 56 days, however, plasma CCK levels in oleic acid-treated rats were significantly high compared with those in control rats. Oleic Acid 50-60 cholecystokinin Rattus norvegicus 36-39 1796181-1 1991 The role played by CCK in the stimulation of pancreatic secretion by duodenal infusion of oleic acid in conscious rats was studied using a potent and specific CCK receptor antagonist. Oleic Acid 90-100 cholecystokinin Rattus norvegicus 19-22 1735364-0 1992 Role of endogenous secretin and cholecystokinin in intraduodenal oleic acid-induced inhibition of gastric acid secretion in rats. Oleic Acid 65-75 cholecystokinin Rattus norvegicus 32-47 1735364-1 1992 We investigated a possible role of endogenous secretin and cholecystokinin (CCK) in inhibition of gastric acid secretion induced by intraduodenal administration of oleic acid in rats. Oleic Acid 164-174 cholecystokinin Rattus norvegicus 76-79 1735364-2 1992 Intraduodenal administration of oleic acid emulsion in a dose of 1 mmol/hr resulted in significant inhibition of gastric acid secretion stimulated by intravenous infusion of pentagastrin (0.3 micrograms/kg/hr), and this was accompanied by an increase in the plasma concentration of both secretin and CCK, from 1.2 +/- 0.08 pM and 20.6 +/- 1.2 pM to 4.3 +/- 0.18 pM and 31.6 +/- 0.9 pM, respectively (P less than 0.001). Oleic Acid 32-42 cholecystokinin Rattus norvegicus 300-303 1796181-5 1991 CCK appears to be directly responsible for the protein and also water response to duodenal infusion of oleic acid, and to be indirectly involved in bicarbonate stimulation. Oleic Acid 103-113 cholecystokinin Rattus norvegicus 0-3 1704631-4 1991 Intraduodenal oleic acid stimulated pancreatic secretion, including volume, bicarbonate, and amylase, and this was accompanied by a significant elevation in the plasma concentrations of secretin and CCK. Oleic Acid 14-24 cholecystokinin Rattus norvegicus 199-202 1704631-5 1991 Intravenous administration of SMS 201-995 in the three different doses described above caused dose-dependent suppression of the increase in pancreatic exocrine secretion as well as the plasma concentration of secretin and CCK induced by intraduodenal infusion of oleic acid. Oleic Acid 263-273 cholecystokinin Rattus norvegicus 222-225 1970707-4 1990 Infusion of intact fat had a small, but nonsignificant, effect (1.4 +/- 0.4 pM), whereas infusion of oleate increased plasma CCK to 3.7 +/- 0.6 pM. Oleic Acid 101-107 cholecystokinin Rattus norvegicus 125-128 2572741-3 1989 The sodium salt of the monounsaturated fatty acid oleic acid (3.5 g) produced a significantly greater integrated CCK response than that of the saturated fatty acid stearic acid (mean [SEM] 103 [41] vs 8[41] pmol.l-1.min). Oleic Acid 50-60 cholecystokinin Rattus norvegicus 113-116 1689684-0 1990 Role of secretin and cholecystokinin in oleic acid-stimulated pancreatic secretion in rats. Oleic Acid 40-50 cholecystokinin Rattus norvegicus 21-36 1689684-1 1990 We investigated the possible role of endogenous secretin and cholecystokinin (CCK) on oleic acid-stimulated pancreatic exocrine secretion in anesthetized rats. Oleic Acid 86-96 cholecystokinin Rattus norvegicus 78-81 1689684-3 1990 Plasma secretin and CCK concentrations also elevated significantly in response to oleic acid, in a dose-related manner (r = 0.721 and 0.546, respectively) (P less than 0.001). Oleic Acid 82-92 cholecystokinin Rattus norvegicus 20-23 1689684-4 1990 There were statistically significant correlations between plasma secretin concentrations and bicarbonate outputs, and between plasma CCK concentrations and amylase outputs in response to oleic acid (P less than 0.01). Oleic Acid 187-197 cholecystokinin Rattus norvegicus 133-136 1689684-5 1990 Potent CCK antagonist, CR 1409 (5 mg/kg.hr) administered intravenously suppressed completely increase in amylase output induced by oleic acid, and partially in juice volume and bicarbonate output. Oleic Acid 131-141 cholecystokinin Rattus norvegicus 7-10 1689684-6 1990 It is concluded that both endogenous secretin and CCK play important roles on oleic acid-induced pancreatic secretion in rats. Oleic Acid 78-88 cholecystokinin Rattus norvegicus 50-53