PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15704291-0 2005 Oleic acid suppresses overexpression of ERBB2 oncogene. Oleic Acid 0-10 erb-b2 receptor tyrosine kinase 2 Homo sapiens 40-45 17168666-3 2006 Our most recent findings reveal that oleic acid (OA; 18:1n-9), the main olive oil"s monounsaturated fatty acid, can suppress the overexpression of HER2 (erbB-2), a well-characterized oncogene playing a key role in the etiology, invasive progression and metastasis in several human cancers. Oleic Acid 37-47 erb-b2 receptor tyrosine kinase 2 Homo sapiens 147-151 16406575-0 2006 A genomic explanation connecting "Mediterranean diet", olive oil and cancer: oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/neu (erbB-2) oncogene promoter in breast, ovarian and stomach cancer cells. Oleic Acid 77-87 erb-b2 receptor tyrosine kinase 2 Homo sapiens 244-247 28959095-1 2017 To study the involvement of compounds stigmasterol and oleic acid isolated from marine sponge Aurora globostellata and docking against the Human Epidermal Growth Factor Receptor-2 in breast cancer. Oleic Acid 55-65 erb-b2 receptor tyrosine kinase 2 Homo sapiens 139-179 28959095-6 2017 The results of the docking studies carried out on HER2 provide an insight for the compound stigmasterol to have drug like properties than oleic acid. Oleic Acid 138-148 erb-b2 receptor tyrosine kinase 2 Homo sapiens 50-54 23588432-6 2012 Herein, oleic acid could suppress the over-expression of HER2 (erbB-2), a well-characterized oncogene which plays a key role in the etiology, invasive progression and metastasis in several human cancers. Oleic Acid 8-18 erb-b2 receptor tyrosine kinase 2 Homo sapiens 57-61 23588432-6 2012 Herein, oleic acid could suppress the over-expression of HER2 (erbB-2), a well-characterized oncogene which plays a key role in the etiology, invasive progression and metastasis in several human cancers. Oleic Acid 8-18 erb-b2 receptor tyrosine kinase 2 Homo sapiens 63-69 17490486-2 2007 While the anti-HER2 oncogene effects of the main omega-9 fatty acid present in EVOO triacylglycerols (i.e., oleic acid) have been recently described, the anti-breast cancer activities of EVOO non-glyceridic constituents--which consist of at least 30 phenolic compounds--remained to be evaluated. Oleic Acid 49-67 erb-b2 receptor tyrosine kinase 2 Homo sapiens 15-19 17490486-2 2007 While the anti-HER2 oncogene effects of the main omega-9 fatty acid present in EVOO triacylglycerols (i.e., oleic acid) have been recently described, the anti-breast cancer activities of EVOO non-glyceridic constituents--which consist of at least 30 phenolic compounds--remained to be evaluated. Oleic Acid 108-118 erb-b2 receptor tyrosine kinase 2 Homo sapiens 15-19 15642702-0 2005 Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification. Oleic Acid 0-10 erb-b2 receptor tyrosine kinase 2 Homo sapiens 79-82 15642702-0 2005 Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification. Oleic Acid 0-10 erb-b2 receptor tyrosine kinase 2 Homo sapiens 223-226 32750194-0 2020 A New Multi-action Pt(IV) Conjugate with Oleate and Cinnamate Ligands Targets Human Epithelial Growth Factor Receptor HER2 in Aggressive Breast Cancer Cells. Oleic Acid 41-47 erb-b2 receptor tyrosine kinase 2 Homo sapiens 118-122 32750194-2 2020 To design an anticancer drug selective for HER2 expressing breast cancer, the new Pt(IV) prodrug with axial oleate and cinnamate ligands was synthesized. Oleic Acid 108-114 erb-b2 receptor tyrosine kinase 2 Homo sapiens 43-47