PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17415471-1	2006	A dose-dependent the effect of 5HT2C-receptor agonist MK-212 on mouse behavior was demonstrated.	6-chloro-2-(1-piperazinyl)pyrazine	54-60	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	31-45	
17141810-3	2007	Subcutaneous injection of mCPP (1 and 3mg/kg) and the preferential 5-HT(2C) receptor agonist MK212 (0.7 and 1mg/kg) induced hypolocomotion during novelty exposure.	6-chloro-2-(1-piperazinyl)pyrazine	93-98	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	67-84	
17141810-5	2007	In contrast, MK212 induced hypolocomotion that was blocked by SB242084, indicating a specific 5-HT(2C) receptor involvement.	6-chloro-2-(1-piperazinyl)pyrazine	13-18	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	94-111	
34560172-4	2022	The results showed that systemic administration of the 5-HT2C receptor agonist MK212 did not affect normal PPI behavior, but reversed the PPI deficits induced by the N-methyl d-aspartate receptor antagonist MK801 in mice.	6-chloro-2-(1-piperazinyl)pyrazine	79-84	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	55-70	
31968217-4	2020	In this study, we discovered that chronic alcohol treatment increased editing of RNA of 5-HT2CR via up-regulating the expression of ADAR2, consequently reducing the release of ATP from astrocytes induced by 5-HT2CR agonist, MK212.	6-chloro-2-(1-piperazinyl)pyrazine	224-229	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	88-95	
31968217-4	2020	In this study, we discovered that chronic alcohol treatment increased editing of RNA of 5-HT2CR via up-regulating the expression of ADAR2, consequently reducing the release of ATP from astrocytes induced by 5-HT2CR agonist, MK212.	6-chloro-2-(1-piperazinyl)pyrazine	224-229	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	207-214	
31968217-6	2020	The increased release of astroglial ATP by MK212 which was suppressed by chronic alcohol consumption, and reduction in ADAR2 activity eliminated the RNA editing of 5-HT2CR increased by alcohol in vitro and recovered the release of ATP from astrocytes induced by MK212.	6-chloro-2-(1-piperazinyl)pyrazine	262-267	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	164-171	
29548885-7	2018	Interestingly, prior injection of SB 242084 (a selective 5-HT2C antagonist) into the amygdala also blocked the MK-212 effects on OAA.	6-chloro-2-(1-piperazinyl)pyrazine	111-117	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	57-63	
27059332-2	2016	The present study examined the effects of intra-dPAG infusion of the serotonin 5-HT2C receptor agonist (MK-212) in the defensive reactions and antinociception in mice with neurophatic pain confronted by a predator.	6-chloro-2-(1-piperazinyl)pyrazine	104-110	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	79-94	
26380122-2	2015	The 5-HT2C receptor agonist MK-212 applied intraperitoneally induced significant dose-dependent reduction of distance traveled in the open field test in CBA/Lac mice.	6-chloro-2-(1-piperazinyl)pyrazine	28-34	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	4-19	
26380122-5	2015	We found that the 5-HT2C receptor stimulation by MK-212 decreased distance traveled in the open field test in CBA/Lac, C57Bl/6, C3H/He, and ICR mice, whereas it failed to affect locomotor activity in DBA/2J, Asn, and Balb/c mice.	6-chloro-2-(1-piperazinyl)pyrazine	49-55	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	18-33