PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7495925-3	1995	MK-212 induced a significant increase in plasma concentrations of cortisol and PRL.	6-chloro-2-(1-piperazinyl)pyrazine	0-6	prolactin	Homo sapiens	79-82	
7495925-0	1995	Effect of pindolol pretreatment on MK-212-induced plasma cortisol and prolactin responses in normal men.	6-chloro-2-(1-piperazinyl)pyrazine	35-41	prolactin	Homo sapiens	70-79	
7495925-4	1995	The MK-212-induced response in plasma cortisol was not diminished by pindolol pretreatment, whereas the MK-212-induced PRL response was significantly inhibited by pindolol pretreatment.	6-chloro-2-(1-piperazinyl)pyrazine	104-110	prolactin	Homo sapiens	119-122	
7495925-5	1995	These data suggest that the MK-212-induced cortisol response may be mediated by 5-HT2A or 5-HT2C receptor activation, or both, despite 5-HT1A inhibition; however, PRL secretion by MK-212 requires 5-HT1A receptor availability as well as 5-HT2A/5-HT2C receptor activation, since blockade of the former appears to blunt the PRL responses to MK-212.	6-chloro-2-(1-piperazinyl)pyrazine	28-34	prolactin	Homo sapiens	163-166	
7495925-5	1995	These data suggest that the MK-212-induced cortisol response may be mediated by 5-HT2A or 5-HT2C receptor activation, or both, despite 5-HT1A inhibition; however, PRL secretion by MK-212 requires 5-HT1A receptor availability as well as 5-HT2A/5-HT2C receptor activation, since blockade of the former appears to blunt the PRL responses to MK-212.	6-chloro-2-(1-piperazinyl)pyrazine	28-34	prolactin	Homo sapiens	321-324	
7495925-5	1995	These data suggest that the MK-212-induced cortisol response may be mediated by 5-HT2A or 5-HT2C receptor activation, or both, despite 5-HT1A inhibition; however, PRL secretion by MK-212 requires 5-HT1A receptor availability as well as 5-HT2A/5-HT2C receptor activation, since blockade of the former appears to blunt the PRL responses to MK-212.	6-chloro-2-(1-piperazinyl)pyrazine	180-186	prolactin	Homo sapiens	163-166	
7495925-5	1995	These data suggest that the MK-212-induced cortisol response may be mediated by 5-HT2A or 5-HT2C receptor activation, or both, despite 5-HT1A inhibition; however, PRL secretion by MK-212 requires 5-HT1A receptor availability as well as 5-HT2A/5-HT2C receptor activation, since blockade of the former appears to blunt the PRL responses to MK-212.	6-chloro-2-(1-piperazinyl)pyrazine	180-186	prolactin	Homo sapiens	163-166	
1756196-4	1991	The plasma PRL, but not the plasma cortisol response, following MK-212 was also significantly lower in the alcoholics.	6-chloro-2-(1-piperazinyl)pyrazine	64-70	prolactin	Homo sapiens	11-14	
7956751-5	1994	However, the plasma cortisol and PRL responses to MK-212 did not differ between the two groups.	6-chloro-2-(1-piperazinyl)pyrazine	50-56	prolactin	Homo sapiens	33-36	
3365458-0	1988	Stimulation of serum cortisol and prolactin secretion in humans by MK-212, a centrally active serotonin agonist.	6-chloro-2-(1-piperazinyl)pyrazine	67-73	prolactin	Homo sapiens	34-43	
3365458-5	1988	The cortisol and prolactin responses to the 40-mg dose of MK-212 were positively correlated (rho = + 0.85, p less than 0.02).	6-chloro-2-(1-piperazinyl)pyrazine	58-64	prolactin	Homo sapiens	17-26	
3365458-8	1988	MK-212 may stimulate the secretion of cortisol and prolactin in humans via a serotonin (5-HT2) receptor mechanism and may be a valuable tool with which to study 5-HT receptor sensitivity in humans.	6-chloro-2-(1-piperazinyl)pyrazine	0-6	prolactin	Homo sapiens	51-60