PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27210033-6 2016 Notably, excess Se exposure up-regulated transcript abundance of aryl hydrocarbon receptor 2 (ahr2), a signalling pathway involved in the toxicity of dioxin-related compounds. Dioxins 150-156 aryl hydrocarbon receptor 2 Danio rerio 65-92 31096425-11 2019 Genes that are implicated in the response to PAHs, PCBs, dioxins and furans (cyp1a, cyp1b1, ahr2) were significantly elevated in the 120 hpf larvae exposed to the B1 and B2 sediments. Dioxins 57-64 aryl hydrocarbon receptor 2 Danio rerio 92-96 29522672-5 2018 Molecular dynamics simulations indicated the interaction between dioxins/dioxin-like compounds (DLCs) and six key amino acid residues in the ligand-binding domain of Ahr2 probably determined the susceptibility to dioxins/DLCs in zebrafish. Dioxins 65-72 aryl hydrocarbon receptor 2 Danio rerio 166-170 29522672-5 2018 Molecular dynamics simulations indicated the interaction between dioxins/dioxin-like compounds (DLCs) and six key amino acid residues in the ligand-binding domain of Ahr2 probably determined the susceptibility to dioxins/DLCs in zebrafish. Dioxins 65-71 aryl hydrocarbon receptor 2 Danio rerio 166-170 29522672-5 2018 Molecular dynamics simulations indicated the interaction between dioxins/dioxin-like compounds (DLCs) and six key amino acid residues in the ligand-binding domain of Ahr2 probably determined the susceptibility to dioxins/DLCs in zebrafish. Dioxins 213-220 aryl hydrocarbon receptor 2 Danio rerio 166-170 27210033-6 2016 Notably, excess Se exposure up-regulated transcript abundance of aryl hydrocarbon receptor 2 (ahr2), a signalling pathway involved in the toxicity of dioxin-related compounds. Dioxins 150-156 aryl hydrocarbon receptor 2 Danio rerio 94-98 9931422-9 1999 In vitro produced zfAhR2 protein dimerizes with the rainbow trout aryl hydrocarbon receptor nuclear translocator (rtARNTb) and binds dioxin response elements derived from the rainbow trout CYP1A gene. Dioxins 133-139 aryl hydrocarbon receptor 2 Danio rerio 18-24 23142599-3 2013 To better understand chemical effects on vitellogenin gene regulation, we tested the hypothesis that activation of the aryl hydrocarbon receptor 2 (AHR2) by dioxin inhibits the estrogen receptor pathway regulation of 3 vitellogenin genes (vtg1-3) in vivo, using zebrafish (Danio rerio) as a model teleost. Dioxins 157-163 aryl hydrocarbon receptor 2 Danio rerio 119-146 23142599-3 2013 To better understand chemical effects on vitellogenin gene regulation, we tested the hypothesis that activation of the aryl hydrocarbon receptor 2 (AHR2) by dioxin inhibits the estrogen receptor pathway regulation of 3 vitellogenin genes (vtg1-3) in vivo, using zebrafish (Danio rerio) as a model teleost. Dioxins 157-163 aryl hydrocarbon receptor 2 Danio rerio 148-152 22194803-0 2011 A dominant negative zebrafish Ahr2 partially protects developing zebrafish from dioxin toxicity. Dioxins 80-86 aryl hydrocarbon receptor 2 Danio rerio 30-34 12130674-8 2002 zfAHR2 can dimerize with zfARNT2b and binds with specificity to dioxin-responsive elements (DREs). Dioxins 64-70 aryl hydrocarbon receptor 2 Danio rerio 0-6 12130674-10 2002 In COS-7 cells expressing zfARNT2b and zfAHR2, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure leads to a significant induction of dioxin-responsive reporter genes. Dioxins 76-82 aryl hydrocarbon receptor 2 Danio rerio 39-45 24084256-3 2013 The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). Dioxins 220-227 aryl hydrocarbon receptor 2 Danio rerio 124-128 11072074-7 2000 In COS-7 cells expressing zfARNT2b and zfAhR2, 10 nM TCDD causes a nine-fold induction of a dioxin responsive reporter gene. Dioxins 92-98 aryl hydrocarbon receptor 2 Danio rerio 39-45 11072074-10 2000 DNA gel shift analysis suggests that the decreased function of zfARNT2a is due to inefficient binding of zfARNT2a/zfAhR2 complexes to dioxin responsive elements. Dioxins 134-140 aryl hydrocarbon receptor 2 Danio rerio 114-120