PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11453672-5 2001 The strong positive association between concentrations of dioxin-like PCB/DD/DFs and non-dioxin-like PCBs will in future epidemiological studies make it difficult to separate Ah receptor-dependent effects from non-Ah receptor-dependent effects. Dioxins 58-64 pyruvate carboxylase Homo sapiens 70-73 12642156-3 2003 The two non-ortho (dioxin-like) PCBs, PCB 126 and PCB 77, showed anti-androgenic properties. Dioxins 19-25 pyruvate carboxylase Homo sapiens 32-35 12642156-3 2003 The two non-ortho (dioxin-like) PCBs, PCB 126 and PCB 77, showed anti-androgenic properties. Dioxins 19-25 pyruvate carboxylase Homo sapiens 38-41 12362388-6 2002 The method allows the chromatographic separation of at least 35 congeners and can therefore be applied to the routine monitoring of the general population for both dioxin-like and non-dioxin-like PCB congeners. Dioxins 184-190 pyruvate carboxylase Homo sapiens 196-199 11783634-2 2001 Using these values, release/inflow ratios of dioxin-like PCB congeners (ratio of the amount released from the incinerator to the amount flowing into the incinerator through waste) were calculated. Dioxins 45-51 pyruvate carboxylase Homo sapiens 57-60 11783634-7 2001 Deposition of dioxin-like PCB congeners 81, 126, 169, and 189 were also found in amounts similar to those released via the waste incinerator emissions. Dioxins 14-20 pyruvate carboxylase Homo sapiens 26-29 11453672-5 2001 The strong positive association between concentrations of dioxin-like PCB/DD/DFs and non-dioxin-like PCBs will in future epidemiological studies make it difficult to separate Ah receptor-dependent effects from non-Ah receptor-dependent effects. Dioxins 89-95 pyruvate carboxylase Homo sapiens 70-73 11748491-2 2001 PCB 126 because of its dioxin-like configuration and high toxicity while 153 because it is one of the most commonly detected congeners in breast milk. Dioxins 23-29 pyruvate carboxylase Homo sapiens 0-3 11375377-3 2001 Increased blood levels of dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin), a PCB-like compound, have recently been reported among subjects with diabetes, suggesting that PCB levels could be similarly elevated. Dioxins 26-32 pyruvate carboxylase Homo sapiens 74-77 11375377-3 2001 Increased blood levels of dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin), a PCB-like compound, have recently been reported among subjects with diabetes, suggesting that PCB levels could be similarly elevated. Dioxins 26-32 pyruvate carboxylase Homo sapiens 167-170 10912239-11 2000 Countries that started to implement measures to reduce dioxin emissions in the late 1980s, such as The Netherlands, United Kingdom and Germany, clearly show decreasing PCDD/PCDF and PCB levels in food and consequently a significantly lower dietary intake of these compounds by almost a factor of 2 within the past 7 years. Dioxins 55-61 pyruvate carboxylase Homo sapiens 182-185 11016874-2 2000 PCB 126 because of its dioxin-like configuration and high toxicity and PCB 153 because it is one of the most commonly detected PCB congeners in breast milk. Dioxins 23-29 pyruvate carboxylase Homo sapiens 0-3 11693948-19 2000 Both dioxin-like and non-dioxin-like PCB congeners have been shown to induce neurobehavioral alterations in animals. Dioxins 25-31 pyruvate carboxylase Homo sapiens 37-40 10903109-5 1999 New data on the dioxin-like PCB emissions are presented for cement kilns and sinter plants. Dioxins 16-22 pyruvate carboxylase Homo sapiens 28-31 9872716-13 1999 Breast-feeding for 6 months contributed to the cumulative PCB/dioxin TEQ intake until 25 years of age, 12% in boys and 14% in girls. Dioxins 62-68 pyruvate carboxylase Homo sapiens 58-61 10092435-5 1999 PCB 77 was the major "dioxin-like" congener in the fish, followed by PCB 126 and then PCB 169. Dioxins 22-28 pyruvate carboxylase Homo sapiens 0-3 9464896-1 1998 The major dioxin-related research activities in the United States Department of Agriculture are 1) a survey of dioxin levels in beef samples collected at 13 experiment stations throughout the United States, 2) a feeding study of eight dioxins, four furans, and three PCB at levels equal to or above levels expected at highly industrialized locations, and 3) metabolism studies of 14C-labeled dioxin congeners. Dioxins 10-16 pyruvate carboxylase Homo sapiens 267-270 9828293-4 1998 New experimental data has revealed that a variety of structural, functional and behaviourial alterations can be induced in rodent species following exposure to PHAHs while a Dutch collaborative PCB/dioxin study has illustrated subtle clinical, endocrine and mental/psychomotor development effects can occur in breast fed infants. Dioxins 198-204 pyruvate carboxylase Homo sapiens 194-197 7850370-0 1994 The Dutch PCB/Dioxin Study. Dioxins 14-20 pyruvate carboxylase Homo sapiens 10-13 8907236-0 1996 Approach to risk assessment of chlorinated dioxins from Yusho PCB poisoning. Dioxins 43-50 pyruvate carboxylase Homo sapiens 62-65 7718310-11 1994 In pregnant women, a significant negative correlation was found between some dioxin and PCB congeners in milk and plasma thyroid hormones, while newborn infants showed higher thyroid stimulating hormone (TSH) at higher levels of dioxin exposure. Dioxins 77-83 pyruvate carboxylase Homo sapiens 88-91 7818291-6 1994 The PCB contribution to "dioxin-like" effects among high consumers of fish (calculated as Nordic TCDD equivalents) was almost 80%, whereas that from PCDD and PCDF was only 20%. Dioxins 25-31 pyruvate carboxylase Homo sapiens 4-7 8628610-11 1996 However, when corrected for confounders, the psychomotor score of the 66% highest-exposed breastfed infants ( > 756 pg total PCB-dioxin toxic equivalent) was negatively influenced by this postnatal exposure to PCBs and dioxins, and was comparable to the psychomotor score of the formula-fed infants. Dioxins 132-138 pyruvate carboxylase Homo sapiens 128-131 8520928-3 1995 In order to investigate an association between dietary intake and PCB and dioxin levels in human milk and PCB levels in maternal and cord plasma, the food intake of 418 Dutch women during pregnancy was recorded using semi-quantitative food frequency questionnaires. Dioxins 74-80 pyruvate carboxylase Homo sapiens 66-69 7850374-0 1994 The Dutch PCB/Dioxin Study. Dioxins 14-20 pyruvate carboxylase Homo sapiens 10-13 8033869-8 1994 We offer some simple molecular recognition models to account for the importance of these different structural features in the structure-activity relationships that permit one to express PCB reactivities in terms of dioxin, thyroxine, and estradiol equivalents. Dioxins 215-221 pyruvate carboxylase Homo sapiens 186-189 33864839-1 2021 PCB 180 is a typical non-dioxin-like polychlorinated biphenyl (NDL-PCB). Dioxins 25-31 pyruvate carboxylase Homo sapiens 0-3 8346970-6 1993 The results demonstrate that the apparent dioxin-like potency of PCB residues in Aroclors, seals, and humans is dominated by three congeners, 3,3",4,4"-tetra-, 2,3,3"-4,4"-, and 3,3",4,4",5-pentachlorobiphenyl (IUPAC nos. Dioxins 42-48 pyruvate carboxylase Homo sapiens 65-68 8187704-11 1994 Because of substantial PCB contribution to dioxin toxic equivalents, total dioxinlike toxicity can only be determined if dioxins, dibenzofurans, and dioxinlike PCBs are measured. Dioxins 43-49 pyruvate carboxylase Homo sapiens 23-26 1669971-3 1991 It appears that "dioxin"-like properties of some PCB congeners are amenable to a TEF treatment that is compatible with that used for CDDs/CDFs. Dioxins 17-23 pyruvate carboxylase Homo sapiens 49-52 15092651-4 1988 The recent isomer-specific analyses suggest that the intrinsic toxicity of PCBs principally resulted from the coplanar PCB congeners which may impose a greater toxic threat than chlorinated dioxins and furans to humans and wildlife. Dioxins 190-197 pyruvate carboxylase Homo sapiens 75-78 34023604-1 2021 2,3",4,4",5-pentachlorodiphenyl (PCB 118), a dioxin-like PCB, is often detected in the environment and is difficult to be aerobically biodegraded. Dioxins 45-51 pyruvate carboxylase Homo sapiens 33-36 31784153-7 2020 In urban site, PCB-52 and dioxin like PCBs (dl-PCBs) have increased from the past observations with maximum PCB-52 concentration in night time samples. Dioxins 26-32 pyruvate carboxylase Homo sapiens 38-41 32388262-6 2020 The mean dioxin-like PCB and polychlorinated naphthalene TEQs were ~8.9 and ~6.6 times higher in stack gases from a SCu equipped with an oxygen-enriched smelting furnace than in stack gases from a SCu with a converter furnace. Dioxins 9-15 pyruvate carboxylase Homo sapiens 21-24 32535446-5 2020 RESULTS: PCB concentrations (mainly non-dioxin-like (ndl)-PCBs) were higher than OCP ones. Dioxins 40-46 pyruvate carboxylase Homo sapiens 9-12 32535446-8 2020 Among the dioxin-like (dl)-PCBs, non-ortho PCB 169, 77 and 126 were assessed in some milk samples; in all areas we detected the mono-ortho PCB 118 and PCB 105. Dioxins 10-16 pyruvate carboxylase Homo sapiens 27-30 32036522-0 2020 Assessment of PCDD/F and dioxin-like PCB levels in environmental and food samples in the vicinity of IZAYDAS waste incinerator plant (WIP): from past to present. Dioxins 25-31 pyruvate carboxylase Homo sapiens 37-40 31733235-2 2020 It was reported that rat CYP1A1 and catfish CYP1A can hydroxylate 3,3",4,4",5-pentachlorobiphenyl (PCB 126) and 3,3",4,4"-tetrachlorobiphenyl (PCB 77), while potential roles of other CYP1 enzymes in the metabolism of dioxin-like (DL) PCBs remain unconfirmed. Dioxins 217-223 pyruvate carboxylase Homo sapiens 99-102 31733235-2 2020 It was reported that rat CYP1A1 and catfish CYP1A can hydroxylate 3,3",4,4",5-pentachlorobiphenyl (PCB 126) and 3,3",4,4"-tetrachlorobiphenyl (PCB 77), while potential roles of other CYP1 enzymes in the metabolism of dioxin-like (DL) PCBs remain unconfirmed. Dioxins 217-223 pyruvate carboxylase Homo sapiens 143-146 31200452-0 2019 Altered Gene Expression in Dioxin-Like and Non-Dioxin-Like PCB Exposed Peripheral Blood Mononuclear Cells. Dioxins 47-53 pyruvate carboxylase Homo sapiens 59-62 31154221-6 2019 Dioxin-like PCBs accounted for 11.0-70.3% and 2.31-54.8% of total PCB residues in soil and air, respectively. Dioxins 0-6 pyruvate carboxylase Homo sapiens 12-15 31200452-3 2019 The PBMCs of a healthy volunteer (male, 56 years old) were exposed to a mixture of dioxin-like (DL)-PCBs (PCB 77, 81, 105, 114, 118, 123, 126, 156, 157, 167, 169, and 189, 250 microg/L resp.) or non-dioxin-like (NDL)-PCBs (PCB 28, 52, 101, 138, 153, 180, 250 microg/L resp.) or single PCB congener (no.28, 138, 153, 180, 250 microg/L resp.). Dioxins 83-89 pyruvate carboxylase Homo sapiens 100-103 30993357-4 2019 In addition, PCB 126 and PCB 169 were found to be the major toxicity contributors of dioxin-like PCBs in the YRDNR, which should require special focus. Dioxins 85-91 pyruvate carboxylase Homo sapiens 13-16 30933768-8 2019 On the other hand, PCDD/F and dioxin-like PCB levels in soil in rural areas, without a contamination source, are normally safe for food producing animals housed outdoors resulting in healthy food (e.g. meat, eggs, milk). Dioxins 30-36 pyruvate carboxylase Homo sapiens 42-45 30993357-4 2019 In addition, PCB 126 and PCB 169 were found to be the major toxicity contributors of dioxin-like PCBs in the YRDNR, which should require special focus. Dioxins 85-91 pyruvate carboxylase Homo sapiens 25-28 30768972-8 2019 Since dioxin-like PCBs may elicit inflammatory cascades through multiple mechanisms, we then pretreated macrophages with both aryl hydrocarbon receptor (AhR) and NF-kappaB antagonists prior to PCB treatment. Dioxins 6-12 pyruvate carboxylase Homo sapiens 18-21 30768972-10 2019 Our data demonstrate the involvement of PCB 126 in macrophage polarization and inflammation, indicating another important role of dioxin-like PCBs in the pathology of atherosclerosis. Dioxins 130-136 pyruvate carboxylase Homo sapiens 40-43 30384297-10 2019 Even though treatment and dechlorination reduced the dioxin-like toxicity of the PCB mixture, this effect might be offset by the incomplete removal of dechlorination products. Dioxins 53-59 pyruvate carboxylase Homo sapiens 81-84 30813950-11 2019 Conversely, PFOA and dioxin-like PCB-167 were associated with 61% (95% CI 35% to 87%) and 22% (95% CI 8% to 35%) more propionic and acetic acid, respectively. Dioxins 21-27 pyruvate carboxylase Homo sapiens 33-36 30572237-1 2019 This research presents release inventories of unintentionally generated dioxin-like polychlorinated biphenyls (dl-PCB) and hexachlorobenzene (HCB), which so far have not been developed or assessed. Dioxins 72-78 pyruvate carboxylase Homo sapiens 114-117 29223911-10 2018 Almost 70% of the 26PCB concentrations was comprised of the dioxin-like PCB congeners with a maximum concentration of 437ng/g at New Moore market in Chennai, followed by Wire Lane (102ng/g), in Mumbai. Dioxins 61-67 pyruvate carboxylase Homo sapiens 21-24 29713743-12 2018 The estimated toxic equivalency of dioxin-like PCBs suggested that PCB-126 is the most toxic contaminant to endanger the human population. Dioxins 35-41 pyruvate carboxylase Homo sapiens 47-50 28699004-4 2018 We show here that PCB126, a dioxin-like PCB, activates a robust proinflammatory state in fat cell precursors (preadipocytes). Dioxins 28-34 pyruvate carboxylase Homo sapiens 18-21 30316459-0 2019 Corrigendum to "Concentrations of dioxin-like PCB congeners in unweathered Aroclors by HRGC/HRMS using EPA Method 1668A" [Chemosphere 54 (2004) 79-87 with Erratum (Chemosphere 58 (2005) 1151)]. Dioxins 34-40 pyruvate carboxylase Homo sapiens 46-49 30022311-6 2018 OCP concentration level in adipose tissue samples for healthy people was 32 times higher than for cancer patient persons, while the TEQ values for dioxin-like PCB concentrations in adipose tissue samples of healthy people was 2.2 times higher than in the samples of cancer-affected patient and the TEQ values for PCDDs/Fs in adipose tissue samples of cancer-affected patient was 3 times higher than in the samples of healthy people. Dioxins 147-153 pyruvate carboxylase Homo sapiens 159-162 29667064-0 2018 Correction to: Formation of brominated and chlorinated dioxins and its prevention during a pilot test of mechanochemical treatment of PCB and PBDE contaminated soil. Dioxins 55-62 pyruvate carboxylase Homo sapiens 134-137 28592194-2 2017 2,3",4,4",5-Pentachlorobiphenyl, known as PCB-118, is a member of coplanar PCBs which renders their structure similar to polychlorinated dibenzo-p-dioxins (PCDDs) and has dioxin-like activity. Dioxins 147-153 pyruvate carboxylase Homo sapiens 42-45 28384582-3 2017 World Health Organization (WHO) toxic equivalency concentrations (WHO TEQ2005) for PCDD/F+dioxin-like (DL) PCB ranged from 2.2pg TEQ2005 g-1 lipid to 27pg TEQ2005 g-1 lipid. Dioxins 90-96 pyruvate carboxylase Homo sapiens 107-110 29848869-8 2018 Maternal exposure to POPs, such as PCB/dioxins and perfluorinated alkyl substances, has affected not only children"s birth size, thyroid functions, and sex hormone levels, but also postnatal neurodevelopment, infection, and allergy among others. Dioxins 39-46 pyruvate carboxylase Homo sapiens 35-38 29848869-10 2018 Gene-environment interactions have been found for smoking, caffeine, folic acid, and PCB/dioxin. Dioxins 89-95 pyruvate carboxylase Homo sapiens 85-88 28947237-3 2017 Detailed analysis of PCB burden of the participants revealed rather high correlations of lower and higher chlorinated as well as dioxin-like PCBs. Dioxins 129-135 pyruvate carboxylase Homo sapiens 21-24 28702904-0 2017 Formation of brominated and chlorinated dioxins and its prevention during a pilot test of mechanochemical treatment of PCB and PBDE contaminated soil. Dioxins 40-47 pyruvate carboxylase Homo sapiens 119-122 27458090-10 2017 Both dioxin and non-dioxin-like PCB congeners decreased EGFR phosphorylation in cell culture. Dioxins 20-26 pyruvate carboxylase Homo sapiens 32-35 27839925-0 2017 Dioxin-like pcb emissions from cement kilns during the use of alternative fuels. Dioxins 0-6 pyruvate carboxylase Homo sapiens 12-15 28661416-4 2017 Dioxin-like PCB congeners (DL-PCBs) were poorly represented in all biological samples, whereas non Dioxin-Like PCB congeners (noDL-PCBs), in particular environmentally widespread congeners (PCB 153, 138, 180), could be detected in almost all samples. Dioxins 0-6 pyruvate carboxylase Homo sapiens 12-15 28661416-4 2017 Dioxin-like PCB congeners (DL-PCBs) were poorly represented in all biological samples, whereas non Dioxin-Like PCB congeners (noDL-PCBs), in particular environmentally widespread congeners (PCB 153, 138, 180), could be detected in almost all samples. Dioxins 0-6 pyruvate carboxylase Homo sapiens 30-33 28661416-4 2017 Dioxin-like PCB congeners (DL-PCBs) were poorly represented in all biological samples, whereas non Dioxin-Like PCB congeners (noDL-PCBs), in particular environmentally widespread congeners (PCB 153, 138, 180), could be detected in almost all samples. Dioxins 0-6 pyruvate carboxylase Homo sapiens 30-33 28270159-8 2017 CONCLUSIONS: This cross-sectional analysis which controlled for collinear exposure to several neurotoxic compounds demonstrated an association between non-dioxin like polychlorinated biphenyl exposure, specifically PCB 146, and lower cognitive functioning, in older adults. Dioxins 155-161 pyruvate carboxylase Homo sapiens 215-218 27839925-3 2017 This paper presents stack emission monitoring of health-critical dl-PCB (dioxin-like polychlorinated biphenyl) congeners during the substitution of alternative fuels at ten Australian cement plants, and to distinguish statistical similarities between other key pollutants (such as polychlorinated dibenzo-p-dioxins and furans (PCDD-F) and hydrogen halogens) and amongst the fuels used. Dioxins 73-79 pyruvate carboxylase Homo sapiens 68-71 26490912-1 2016 Dioxin-like polychlorinated biphenyl (dl-PCB) concentrations in ambient air and soil in Shanghai, China, were measured to allow seasonal and spatial differences in the dl-PCB concentrations, profiles, distributions, fugacity fractions, and air-soil fluxes to be determined. Dioxins 0-6 pyruvate carboxylase Homo sapiens 41-44 27131450-5 2016 The generation of dioxin-like PCBs (Co- or dl-PCB) was also analysed. Dioxins 18-24 pyruvate carboxylase Homo sapiens 30-33 26970589-6 2016 Exposure to dioxins and dioxin-like PCBs (dl-compounds) was expressed in total toxic equivalents (TEQ), and PCB-153 was used as marker for non-dioxin-like PCBs (ndlPCBs). Dioxins 24-30 pyruvate carboxylase Homo sapiens 36-39 27503630-6 2016 Predominance of dioxin like PCBs, PCB-l14, -118 and -126 in the e-waste metal recovery sites were presumably due to combustion and pyrolytic processes performed during recycling of electrical components. Dioxins 16-22 pyruvate carboxylase Homo sapiens 28-31 26970589-3 2016 OBJECTIVES: The aim was to examine the association between maternal low level dietary exposure to dioxins and PCB during pregnancy and language development in 3year old children in a large group of mother-child pairs participating in the Norwegian Mother and Child Cohort Study (MoBa). Dioxins 98-105 pyruvate carboxylase Homo sapiens 110-113 26936477-8 2016 In conclusion, our study shows for the first time that exposure to a dioxin-like PCB adversely affects skeletal muscle glucose metabolism. Dioxins 69-75 pyruvate carboxylase Homo sapiens 81-84 25893464-4 2016 The sum of median concentrations of tri + tetra-chlorinated PCB was almost ten times higher in the exposed group than in the unexposed, and sums of dioxin-like and non-dioxin-like PCB were both relatively increased by 60 % in the exposed group. Dioxins 168-174 pyruvate carboxylase Homo sapiens 180-183 24162035-7 2014 RESULTS: Maternal serum concentrations of HCB and dioxin-like PCB-118 were positively associated with offspring asthma medication use after 20 years of follow-up (p for trend<0.05). Dioxins 50-56 pyruvate carboxylase Homo sapiens 62-65 25659934-0 2015 Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways. Dioxins 4-10 pyruvate carboxylase Homo sapiens 43-46 25659934-0 2015 Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways. Dioxins 4-10 pyruvate carboxylase Homo sapiens 52-55 25659934-0 2015 Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways. Dioxins 4-10 pyruvate carboxylase Homo sapiens 52-55 25668756-3 2015 Results from this study show that a quinone-derivative (1-(4-Chlorophenyl)-benzo-2,5-quinone; 4-ClBQ) of a non-dioxin like PCB (PCB3) also activates AhR-signaling. Dioxins 111-117 pyruvate carboxylase Homo sapiens 123-126 25668756-3 2015 Results from this study show that a quinone-derivative (1-(4-Chlorophenyl)-benzo-2,5-quinone; 4-ClBQ) of a non-dioxin like PCB (PCB3) also activates AhR-signaling. Dioxins 111-117 pyruvate carboxylase Homo sapiens 128-132 25663396-0 2015 Dioxin-like PCB levels in maternal and umbilical cord sera of people living near dump sites in southern Italy: a pilot study of biomonitoring. Dioxins 0-6 pyruvate carboxylase Homo sapiens 12-15 24967557-7 2014 Moreover, when we analyzed the results of the congeners (non-dioxin-like PCBs and dioxin-like PCBs), the levels of non-dioxin-like PCB congeners ranged from 5.7 to 103469 mug kg(-1) and the levels of dioxin-like PCB congeners ranged from 0.5 to 4992 mug kg(-1). Dioxins 61-67 pyruvate carboxylase Homo sapiens 73-76 24967557-7 2014 Moreover, when we analyzed the results of the congeners (non-dioxin-like PCBs and dioxin-like PCBs), the levels of non-dioxin-like PCB congeners ranged from 5.7 to 103469 mug kg(-1) and the levels of dioxin-like PCB congeners ranged from 0.5 to 4992 mug kg(-1). Dioxins 82-88 pyruvate carboxylase Homo sapiens 94-97 24967557-7 2014 Moreover, when we analyzed the results of the congeners (non-dioxin-like PCBs and dioxin-like PCBs), the levels of non-dioxin-like PCB congeners ranged from 5.7 to 103469 mug kg(-1) and the levels of dioxin-like PCB congeners ranged from 0.5 to 4992 mug kg(-1). Dioxins 82-88 pyruvate carboxylase Homo sapiens 94-97 24967557-7 2014 Moreover, when we analyzed the results of the congeners (non-dioxin-like PCBs and dioxin-like PCBs), the levels of non-dioxin-like PCB congeners ranged from 5.7 to 103469 mug kg(-1) and the levels of dioxin-like PCB congeners ranged from 0.5 to 4992 mug kg(-1). Dioxins 82-88 pyruvate carboxylase Homo sapiens 94-97 24774064-9 2014 Fruit and vegetable intake, as reflected by serum carotenoid concentrations, predicted notably reduced probability of dioxin-like PCB-associated risk for type 2 diabetes. Dioxins 118-124 pyruvate carboxylase Homo sapiens 130-133 24486495-4 2014 Toxicological evaluation by TCA and TEQ methods, conducted for the first time in Venice air samples, identified BaP, PCB-126 and PCB-169 as the most important contributors to the total carcinogenic activity of PAHs and the total dioxin-like activity of PCBs and PCNs. Dioxins 229-235 pyruvate carboxylase Homo sapiens 129-132 24220260-0 2014 PCDD/F and dioxin-like PCB concentrations during municipal solid waste biomethanation and subsequent composting. Dioxins 11-17 pyruvate carboxylase Homo sapiens 23-26 24220260-1 2014 PCDD/F and dioxin-like PCB concentrations were compared in different samples of a municipal solid waste (MSW) treatment plant: the initial MSW fraction that enters the biomethanation from the digester, the semi-solid digestate obtained after biomethanation of MSW, and the solids after composting the digestate since the final product is destined for land application and special attention must be paid to these compounds for environmental considerations. Dioxins 11-17 pyruvate carboxylase Homo sapiens 23-26 24275543-8 2014 We found a significant interaction between dioxin-like PCB concentration and age in association with cognitive score (p=0.04). Dioxins 43-49 pyruvate carboxylase Homo sapiens 55-58 25304490-4 2015 PCB126 is a dioxin-like PCB and a potent aryl hydrocarbon receptor (AhR) agonist. Dioxins 12-18 pyruvate carboxylase Homo sapiens 0-3 25288548-3 2014 The average concentration of PCBs (7 indicator PCB and 12 dioxin like-PCB congeners) was (16.2+-9.25) pg/g, and WHO-TEQ average concentration was 0.043+-0.049pgWHO-TEQ/g. Dioxins 59-65 pyruvate carboxylase Homo sapiens 30-33 24162035-10 2014 Weak positive associations were also estimated for PCB-156 and the non-dioxin-like PCBs (PCBs 138, 153, 170, 180). Dioxins 71-77 pyruvate carboxylase Homo sapiens 51-54 23419585-3 2013 PCB congeners were summed separately for dioxin-like and nondioxin-like PCBs; the former were weighted for toxic equivalent factors. Dioxins 41-47 pyruvate carboxylase Homo sapiens 0-3 23491026-6 2013 Using the optimization approach to construct weighted quartile scores, the dioxin like PCB, the non-dioxin like PCB and metal class-level scores were significantly associated with elevated ALT. Dioxins 75-81 pyruvate carboxylase Homo sapiens 87-90 22750796-4 2012 The pooled samples were analysed for 17 PCDD/Fs and 36 PCB congeners, and from these data, total toxic equivalent concentrations (TEQ(2005 PCDD/F+Dioxin-like [DL]-PCB)) were estimated. Dioxins 146-152 pyruvate carboxylase Homo sapiens 163-166 23032644-14 2012 These models underline the value of dietary intake data for use in investigations of associations between dioxin and PCB exposure and health outcomes in large epidemiological studies with limited biomaterial for chemical analysis. Dioxins 106-112 pyruvate carboxylase Homo sapiens 117-120 22564984-5 2012 A negative relationship remained between PCB 118 and SHBG (p<0.01), and relationships of dioxin-like PCBs with SHBG and total testosterone, and between PCB 118 and total testosterone, were suggestive. Dioxins 92-98 pyruvate carboxylase Homo sapiens 104-107 24278597-7 2012 While non-dioxin-like-PCB (PCB-52 and PCB-4) induced a translocation of PKC-alpha and -epsilon from cytosol to membrane fraction, dioxin-like PCBs (PCB-126, -169, -114, -157) had no effects. Dioxins 10-16 pyruvate carboxylase Homo sapiens 22-25 22842592-1 2012 In this work, a reliable methodology for the simultaneous analysis of PCDD/PCDF and dioxin-like PCB (dl-PCB) in flue gas emissions collected using continuous sampling devices is proposed. Dioxins 84-90 pyruvate carboxylase Homo sapiens 96-99 22842592-1 2012 In this work, a reliable methodology for the simultaneous analysis of PCDD/PCDF and dioxin-like PCB (dl-PCB) in flue gas emissions collected using continuous sampling devices is proposed. Dioxins 84-90 pyruvate carboxylase Homo sapiens 104-107 23082663-1 2012 The indigenous people of coastal areas show a low percentage of low chlorinated and dioxin-like PCB congeners (as opposed to mainland aborigines) with a significant proportion of the "triad" in the amount of PCBs. Dioxins 84-90 pyruvate carboxylase Homo sapiens 96-99 24278597-7 2012 While non-dioxin-like-PCB (PCB-52 and PCB-4) induced a translocation of PKC-alpha and -epsilon from cytosol to membrane fraction, dioxin-like PCBs (PCB-126, -169, -114, -157) had no effects. Dioxins 10-16 pyruvate carboxylase Homo sapiens 27-30 24278597-7 2012 While non-dioxin-like-PCB (PCB-52 and PCB-4) induced a translocation of PKC-alpha and -epsilon from cytosol to membrane fraction, dioxin-like PCBs (PCB-126, -169, -114, -157) had no effects. Dioxins 10-16 pyruvate carboxylase Homo sapiens 27-30 24278597-7 2012 While non-dioxin-like-PCB (PCB-52 and PCB-4) induced a translocation of PKC-alpha and -epsilon from cytosol to membrane fraction, dioxin-like PCBs (PCB-126, -169, -114, -157) had no effects. Dioxins 10-16 pyruvate carboxylase Homo sapiens 27-30 24278597-7 2012 While non-dioxin-like-PCB (PCB-52 and PCB-4) induced a translocation of PKC-alpha and -epsilon from cytosol to membrane fraction, dioxin-like PCBs (PCB-126, -169, -114, -157) had no effects. Dioxins 130-136 pyruvate carboxylase Homo sapiens 22-25 24278597-7 2012 While non-dioxin-like-PCB (PCB-52 and PCB-4) induced a translocation of PKC-alpha and -epsilon from cytosol to membrane fraction, dioxin-like PCBs (PCB-126, -169, -114, -157) had no effects. Dioxins 130-136 pyruvate carboxylase Homo sapiens 27-30 24278597-7 2012 While non-dioxin-like-PCB (PCB-52 and PCB-4) induced a translocation of PKC-alpha and -epsilon from cytosol to membrane fraction, dioxin-like PCBs (PCB-126, -169, -114, -157) had no effects. Dioxins 130-136 pyruvate carboxylase Homo sapiens 27-30 24278597-7 2012 While non-dioxin-like-PCB (PCB-52 and PCB-4) induced a translocation of PKC-alpha and -epsilon from cytosol to membrane fraction, dioxin-like PCBs (PCB-126, -169, -114, -157) had no effects. Dioxins 130-136 pyruvate carboxylase Homo sapiens 27-30 22280929-9 2012 For the dioxin-like PCBs, PCB 118 was the dominant (0.97 ng/g lipid). Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 22407850-3 2012 Total PCB and dioxin-like PCB (DL-PCB) levels were not significantly different between wild-caught and farm-raised shrimp, and the distribution of total PCB levels did not vary considerably by country of origin although significant differences were observed in some cases. Dioxins 14-20 pyruvate carboxylase Homo sapiens 26-29 22407850-3 2012 Total PCB and dioxin-like PCB (DL-PCB) levels were not significantly different between wild-caught and farm-raised shrimp, and the distribution of total PCB levels did not vary considerably by country of origin although significant differences were observed in some cases. Dioxins 14-20 pyruvate carboxylase Homo sapiens 26-29 22407850-3 2012 Total PCB and dioxin-like PCB (DL-PCB) levels were not significantly different between wild-caught and farm-raised shrimp, and the distribution of total PCB levels did not vary considerably by country of origin although significant differences were observed in some cases. Dioxins 14-20 pyruvate carboxylase Homo sapiens 26-29 20835891-0 2011 PCDD/F and dioxin-like PCB profiles in soils amended with sewage sludge, compost, farmyard manure, and mineral fertilizer since 1962. Dioxins 11-17 pyruvate carboxylase Homo sapiens 23-26 21979385-1 2011 We have studied the effects of dioxin-like 3,3",4,4"-tetrachlorobiphenyl (PCB-77) on developmental effects related to angiogenesis and osteogenesis during early life-stages of salmon. Dioxins 31-37 pyruvate carboxylase Homo sapiens 74-77 21858706-3 2011 PCB congeners pattern of marine organism were characterized by 5-6 CB chlorinated compounds, and the world health organization total dioxin equivalents of PCBs in organism ranged from 1.45 to 88.26 pg/g lipid. Dioxins 133-139 pyruvate carboxylase Homo sapiens 0-3 21726892-4 2011 The PCB baseline concentration (sum of seven PCB indicators (Sigma(7)PCB(ind))) determined on tree barks from a remote area in the Vosges mountains is 4 ng g(-1) and corresponds to 0.36 x 10(-3)ng toxic equivalent (TEQ) g(-1) for the dioxin-like PCBs (DL-PCBs). Dioxins 234-240 pyruvate carboxylase Homo sapiens 4-7 21726892-8 2011 However, very close to this incinerator lowest TEQ dioxin-like PCB (TEQ(DL-PCB)) values of 0.006 ng TEQ g(-1) have been found. Dioxins 51-57 pyruvate carboxylase Homo sapiens 63-66 21616713-8 2011 Among the dioxin-like PCBs, PCB 118, PCB 156 and PCB 167 were detectable in 74-98% of all samples. Dioxins 10-16 pyruvate carboxylase Homo sapiens 22-25 21616713-8 2011 Among the dioxin-like PCBs, PCB 118, PCB 156 and PCB 167 were detectable in 74-98% of all samples. Dioxins 10-16 pyruvate carboxylase Homo sapiens 28-31 21616713-8 2011 Among the dioxin-like PCBs, PCB 118, PCB 156 and PCB 167 were detectable in 74-98% of all samples. Dioxins 10-16 pyruvate carboxylase Homo sapiens 28-31 22004731-3 2011 The sums of the concentrations of 56 non-dioxin-like PCB congeners that were measured in the subjects" blood and breast milk were 16-326 (mean: 107, median: 100) and 12-252 (mean: 73, median: 67) ng g(-1) lipid, respectively. Dioxins 41-47 pyruvate carboxylase Homo sapiens 53-56 20840854-7 2010 A dioxin-like PCB (DL-PCB 126) was used as reference and gave results that were predictable from previous studies, i.e. it attenuated BP-induced p53 response and apoptosis. Dioxins 2-8 pyruvate carboxylase Homo sapiens 14-17 21187307-7 2011 Boys in the highest exposure quintile of the sum of dioxin and PCB concentrations and total TEQs had a significant decrease in mean BMI z scores of 0.67 for dioxins and TEQs and 1.04 for PCBs, compared with boys in the lowest exposure quintile. Dioxins 157-164 pyruvate carboxylase Homo sapiens 63-66 20840854-7 2010 A dioxin-like PCB (DL-PCB 126) was used as reference and gave results that were predictable from previous studies, i.e. it attenuated BP-induced p53 response and apoptosis. Dioxins 2-8 pyruvate carboxylase Homo sapiens 19-29 20541864-4 2010 The PCDD/F, dioxin-like PCB, PCB and PAH concentrations in this input waste mix were more than hundred times higher than in the usual waste feed of the incinerator (30% RFD and 70% WWT sludge). Dioxins 12-18 pyruvate carboxylase Homo sapiens 24-27 19261331-10 2010 These modified reaction conditions allow the synthesis of large quantities of pure, non-dioxin-like PCB congeners and their sulfur-containing metabolites for environmental and toxicological studies by overcoming problems associated with classical PCB synthesis strategies. Dioxins 88-94 pyruvate carboxylase Homo sapiens 100-103 19261331-10 2010 These modified reaction conditions allow the synthesis of large quantities of pure, non-dioxin-like PCB congeners and their sulfur-containing metabolites for environmental and toxicological studies by overcoming problems associated with classical PCB synthesis strategies. Dioxins 88-94 pyruvate carboxylase Homo sapiens 247-250 20598339-5 2010 The WHO-TEQ of dioxin-like PCB and PBDD/Fs counted for 8.9% and 16% of total TEQ (summed over PCDD/Fs, PBDD/Fs, and dioxin-like PCBs), respectively, suggesting that the atmospheric concentrations of dioxin and dioxin-like compounds should be regulated together because of the persistence and toxicity of PBDD/Fs and dioxin-like PCBs. Dioxins 15-21 pyruvate carboxylase Homo sapiens 27-30 20696431-9 2010 All toxic, dioxin-like PCBs, with the exception of PCB 118 that overlaps with PCB 106, were resolved by the apolar/ionic liquid series while on the apolar/polar column series three toxic PCBs overlapped (105+127, 81+148 and 118+106). Dioxins 11-17 pyruvate carboxylase Homo sapiens 23-26 20731829-11 2010 Evidence from this and other studies suggests that prenatal dioxin-like PCB exposure, including mono-ortho congeners, may interfere with brain development in utero. Dioxins 60-66 pyruvate carboxylase Homo sapiens 72-75 20598339-5 2010 The WHO-TEQ of dioxin-like PCB and PBDD/Fs counted for 8.9% and 16% of total TEQ (summed over PCDD/Fs, PBDD/Fs, and dioxin-like PCBs), respectively, suggesting that the atmospheric concentrations of dioxin and dioxin-like compounds should be regulated together because of the persistence and toxicity of PBDD/Fs and dioxin-like PCBs. Dioxins 116-122 pyruvate carboxylase Homo sapiens 27-30 20598339-5 2010 The WHO-TEQ of dioxin-like PCB and PBDD/Fs counted for 8.9% and 16% of total TEQ (summed over PCDD/Fs, PBDD/Fs, and dioxin-like PCBs), respectively, suggesting that the atmospheric concentrations of dioxin and dioxin-like compounds should be regulated together because of the persistence and toxicity of PBDD/Fs and dioxin-like PCBs. Dioxins 116-122 pyruvate carboxylase Homo sapiens 27-30 20598339-5 2010 The WHO-TEQ of dioxin-like PCB and PBDD/Fs counted for 8.9% and 16% of total TEQ (summed over PCDD/Fs, PBDD/Fs, and dioxin-like PCBs), respectively, suggesting that the atmospheric concentrations of dioxin and dioxin-like compounds should be regulated together because of the persistence and toxicity of PBDD/Fs and dioxin-like PCBs. Dioxins 116-122 pyruvate carboxylase Homo sapiens 27-30 20598339-5 2010 The WHO-TEQ of dioxin-like PCB and PBDD/Fs counted for 8.9% and 16% of total TEQ (summed over PCDD/Fs, PBDD/Fs, and dioxin-like PCBs), respectively, suggesting that the atmospheric concentrations of dioxin and dioxin-like compounds should be regulated together because of the persistence and toxicity of PBDD/Fs and dioxin-like PCBs. Dioxins 116-122 pyruvate carboxylase Homo sapiens 27-30 19850319-4 2010 The sums of the concentrations of 56 non-dioxin-like PCB congeners that were measured in the subjects" blood and breast milk were 43-445 (mean: 120, median: 106) and 34-366 (mean: 90, median: 81) ng g(-1)lipid, respectively, indicating that the total TEQ concentration and the total concentration of 56 non-dioxin-like PCB congeners in the maternal blood were notably higher than those in the breast milk. Dioxins 41-47 pyruvate carboxylase Homo sapiens 53-56 20384380-5 2010 In multivariate regression models where otoacoustic measures were modeled as a function of log (base 10) PCB concentrations with adjustment for gender, age, and site of examination, dioxin-like PCBs, nondioxin-like PCBs and a PCB grouping targeting upregulation of hepatic uridine 5"-diphospho-glucuronosyltransferase were significantly associated with lower TEOAE powers at 1000 and 1500 Hz. Dioxins 182-188 pyruvate carboxylase Homo sapiens 194-197 19959279-10 2010 The dioxin-like PCB-TEQ had concentrations ranging from 0.03 to 0.08 pg TEQ g(-1) dw, mainly from PCB126. Dioxins 4-10 pyruvate carboxylase Homo sapiens 16-19 20176394-4 2010 Higher PCDD/F concentrations were observed in the winter, whereas higher dioxin-like PCB concentrations were found in the summer. Dioxins 73-79 pyruvate carboxylase Homo sapiens 85-88 19850319-5 2010 Statistically significant correlations were observed between maternal age and the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs or the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and significant correlations were also observed between maternal age and the total TEQ concentration of these dioxin-like compounds or the total concentration of 56 PCB congeners in breast milk. Dioxins 127-133 pyruvate carboxylase Homo sapiens 139-142 19850319-5 2010 Statistically significant correlations were observed between maternal age and the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs or the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and significant correlations were also observed between maternal age and the total TEQ concentration of these dioxin-like compounds or the total concentration of 56 PCB congeners in breast milk. Dioxins 181-187 pyruvate carboxylase Homo sapiens 193-196 19850319-5 2010 Statistically significant correlations were observed between maternal age and the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs or the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and significant correlations were also observed between maternal age and the total TEQ concentration of these dioxin-like compounds or the total concentration of 56 PCB congeners in breast milk. Dioxins 181-187 pyruvate carboxylase Homo sapiens 193-196 19850319-6 2010 The total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs in maternal blood showed a close correlation to that in subjects" breast milk, and there was also good correlation between the total concentration of 56 non-dioxin-like PCB congeners in maternal blood and that in subjects" breast milk. Dioxins 49-55 pyruvate carboxylase Homo sapiens 61-64 19850319-7 2010 Pearson and Spearman correlation analyses showed a relationship between the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs and the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and also showed an association between the total TEQ concentration of these dioxin-like compounds and the total concentration of 56 PCB congeners in breast milk. Dioxins 121-127 pyruvate carboxylase Homo sapiens 133-136 19850319-7 2010 Pearson and Spearman correlation analyses showed a relationship between the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs and the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and also showed an association between the total TEQ concentration of these dioxin-like compounds and the total concentration of 56 PCB congeners in breast milk. Dioxins 121-127 pyruvate carboxylase Homo sapiens 188-191 19850319-7 2010 Pearson and Spearman correlation analyses showed a relationship between the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs and the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and also showed an association between the total TEQ concentration of these dioxin-like compounds and the total concentration of 56 PCB congeners in breast milk. Dioxins 176-182 pyruvate carboxylase Homo sapiens 133-136 19850319-7 2010 Pearson and Spearman correlation analyses showed a relationship between the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs and the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and also showed an association between the total TEQ concentration of these dioxin-like compounds and the total concentration of 56 PCB congeners in breast milk. Dioxins 176-182 pyruvate carboxylase Homo sapiens 188-191 19850319-7 2010 Pearson and Spearman correlation analyses showed a relationship between the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs and the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and also showed an association between the total TEQ concentration of these dioxin-like compounds and the total concentration of 56 PCB congeners in breast milk. Dioxins 176-182 pyruvate carboxylase Homo sapiens 133-136 19850319-7 2010 Pearson and Spearman correlation analyses showed a relationship between the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs and the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and also showed an association between the total TEQ concentration of these dioxin-like compounds and the total concentration of 56 PCB congeners in breast milk. Dioxins 176-182 pyruvate carboxylase Homo sapiens 188-191 19850319-10 2010 These findings suggested that hexaCB-153 may be an indicator of total TEQ concentrations of PCDDs, PCDFs, and dioxin-like PCBs and total concentrations of 56 non-dioxin-like PCB congeners in blood and breast milk of primiparous mothers. Dioxins 110-116 pyruvate carboxylase Homo sapiens 122-125 19744782-3 2009 PCB-77 concentration was the highest among dioxin-like PCBs and PCB-126 contributed mostly to the WHO-TEQ. Dioxins 43-49 pyruvate carboxylase Homo sapiens 0-3 19744782-3 2009 PCB-77 concentration was the highest among dioxin-like PCBs and PCB-126 contributed mostly to the WHO-TEQ. Dioxins 43-49 pyruvate carboxylase Homo sapiens 55-58 19744782-4 2009 The ratios of dioxin-like PCBs in the total PCB concentrations in the flue gas varied between 11.7% and 26.0% (the average value is 18.7%). Dioxins 14-20 pyruvate carboxylase Homo sapiens 26-29 19588848-1 2009 PCB and dioxin-like PCB (DL-PCB) in 28 umbilical cords preserved from the time when 3 Yusho victims and 11 healthy subjects gave birth were examined in order to investigate the pollution evaluation with both the compounds in Yusho victims on the basis of the analytical value. Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 19375780-6 2009 Qualitative and quantitative measurements of 49 PCB congeners was obtained by HRGC-ECD analysis and total dioxin-like activity using the CAFLUX bioassay. Dioxins 106-112 pyruvate carboxylase Homo sapiens 48-51 19588848-1 2009 PCB and dioxin-like PCB (DL-PCB) in 28 umbilical cords preserved from the time when 3 Yusho victims and 11 healthy subjects gave birth were examined in order to investigate the pollution evaluation with both the compounds in Yusho victims on the basis of the analytical value. Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 18166985-4 2008 Adipose tissue samples were analyzed for PCDD/F and 12 dioxin-like PCB congeners using high-resolution gas chromatography/high-resolution mass spectrometry. Dioxins 55-61 pyruvate carboxylase Homo sapiens 67-70 19058852-0 2009 Dioxin and dioxin-like PCB profiles in the serum of industrial and municipal waste incinerator workers in Korea. Dioxins 11-17 pyruvate carboxylase Homo sapiens 23-26 18718631-11 2008 Among the non-dioxin-like PCB congeners measured in the present study, hexaCB-138, heptaCB-170, heptaCB-180, and heptaCB-182/heptaCB-187 also showed high ratios to total concentrations of 58 non-dioxin-like PCB congeners detected in the blood of primiparous and multiparous mothers. Dioxins 14-20 pyruvate carboxylase Homo sapiens 26-29 18718631-11 2008 Among the non-dioxin-like PCB congeners measured in the present study, hexaCB-138, heptaCB-170, heptaCB-180, and heptaCB-182/heptaCB-187 also showed high ratios to total concentrations of 58 non-dioxin-like PCB congeners detected in the blood of primiparous and multiparous mothers. Dioxins 14-20 pyruvate carboxylase Homo sapiens 207-210 18718631-11 2008 Among the non-dioxin-like PCB congeners measured in the present study, hexaCB-138, heptaCB-170, heptaCB-180, and heptaCB-182/heptaCB-187 also showed high ratios to total concentrations of 58 non-dioxin-like PCB congeners detected in the blood of primiparous and multiparous mothers. Dioxins 195-201 pyruvate carboxylase Homo sapiens 26-29 18718631-12 2008 With regard to the relationship between the total concentrations of 58 non-dioxin-like PCB congeners in maternal blood and the number of deliveries or the age of primiparous and multifarious mothers, the total levels of these PCB congeners tended to decreases with increases in the number of deliveries and significantly increased with increasing maternal age in both groups. Dioxins 75-81 pyruvate carboxylase Homo sapiens 87-90 18718631-12 2008 With regard to the relationship between the total concentrations of 58 non-dioxin-like PCB congeners in maternal blood and the number of deliveries or the age of primiparous and multifarious mothers, the total levels of these PCB congeners tended to decreases with increases in the number of deliveries and significantly increased with increasing maternal age in both groups. Dioxins 75-81 pyruvate carboxylase Homo sapiens 226-229 18795168-5 2008 OBJECTIVES: We aimed to identify the functional TR domain responsible for the PCB-mediated suppression of TR action by comparing the magnitude of suppression using several representative PCB/dioxin congeners. Dioxins 191-197 pyruvate carboxylase Homo sapiens 78-81 18718631-4 2008 Among the 197 non-dioxin-like PCB congeners, 58 congeners were identified in the blood of pregnant women. Dioxins 18-24 pyruvate carboxylase Homo sapiens 30-33 18718631-5 2008 The arithmetic mean total concentrations of 58 non-dioxin-like PCB congeners in the blood of primiparous and multiparous mothers in Sapporo City were 42.2-329.3 (mean: 114.5, median: 98.6) and 31.5-258.0 (mean: 100.3, median: 91.4)ngg(-1)lipid, respectively. Dioxins 51-57 pyruvate carboxylase Homo sapiens 63-66 18768207-4 2008 Among 197 non-dioxin-like PCB congeners, 56 were identified in the blood of elderly residents. Dioxins 14-20 pyruvate carboxylase Homo sapiens 26-29 18166985-7 2008 Concentrations of each of the PCDD/F and dioxin-like PCB congeners were compared in fertile and infertile groups among themselves, and no statistical significance was obtained (p > 0.05), except 2,3,7,8-tetrachlorodibenzofuran (p = 0.0029) and 1,2,3,4,6,7,8,9-octachlorodibenzofuran (p = 0.01). Dioxins 41-47 pyruvate carboxylase Homo sapiens 53-56 18155262-15 2008 Although not conclusive, our findings represent the first study showing the activation of estrogenic responses by a dioxin-like PCB in fish in vitro system and resemble the "ER-hijacking" hypothesis that was recently proposed. Dioxins 116-122 pyruvate carboxylase Homo sapiens 128-131 18001814-1 2008 PCDD/F and dioxin-like PCB were measured in 142 air samples of Hong Kong. Dioxins 11-17 pyruvate carboxylase Homo sapiens 23-26 18001814-4 2008 A higher WHO-TEQ value of dioxin-like PCB (mainly attributed to the relatively higher WHO-TEQ value of PCB 126) in Yuen Long during winter, compared with other months, could also be related to the regional transport by the winter monsoon wind and the low mixing height in winter. Dioxins 26-32 pyruvate carboxylase Homo sapiens 38-41 18001814-4 2008 A higher WHO-TEQ value of dioxin-like PCB (mainly attributed to the relatively higher WHO-TEQ value of PCB 126) in Yuen Long during winter, compared with other months, could also be related to the regional transport by the winter monsoon wind and the low mixing height in winter. Dioxins 26-32 pyruvate carboxylase Homo sapiens 103-106 18001814-5 2008 Spatially, air concentrations of PCDD/F and dioxin-like PCB demonstrated a west-to-east gradient (with Yuen Long>Tsuen Wan>Tap Mun). Dioxins 44-50 pyruvate carboxylase Homo sapiens 56-59 18001814-6 2008 It is suggested that PCDD/F and dioxin-like PCB were transported into the western airshed of Hong Kong from the Pearl River Delta by land-sea breeze circulation and confined to the northwestern part, due to the blocking effect of the northwestern airshed in Hong Kong. Dioxins 32-38 pyruvate carboxylase Homo sapiens 44-47 18155262-4 2008 Firstly, salmon primary hepatocytes were exposed to the dioxin-like PCB126 at 1, 10 and 50 nM [corrected] and ER agonist nonylphenol (NP) at 5 and 10 microM, singly or in combination. Dioxins 56-62 pyruvate carboxylase Homo sapiens 68-71 18313043-9 2008 Serum TSH increased with hair and blood Hg concentrations and was highest among those in the highest 50th percentile for both Hg and dioxin-like PCB congeners compared to the others. Dioxins 133-139 pyruvate carboxylase Homo sapiens 145-148 18045642-8 2008 Twelve dioxin-like PCBs contributed around 8% of the total PCB exposure, and all were present in all study subjects. Dioxins 7-13 pyruvate carboxylase Homo sapiens 19-22 21783853-0 2008 The Belgian PCB/dioxin crisis-8 years later An overview. Dioxins 16-22 pyruvate carboxylase Homo sapiens 12-15 21783853-3 2008 This has resulted in a major food crisis, known worldwide as the "Belgian PCB/dioxin crisis". Dioxins 78-84 pyruvate carboxylase Homo sapiens 74-77 17722095-5 2007 Several dioxin-like PCB congeners were associated with increased risk of NHL, including dioxin-like PCB nos. Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 18438020-1 2008 A method for the determination of dioxin like polychlorinated biphenyl (DL-PCB) residues in milk has been developed using high resolution gas chromatography coupled with ion trap mass spectrometry (GC-MS/MS-IT). Dioxins 34-40 pyruvate carboxylase Homo sapiens 75-78 17722095-5 2007 Several dioxin-like PCB congeners were associated with increased risk of NHL, including dioxin-like PCB nos. Dioxins 88-94 pyruvate carboxylase Homo sapiens 20-23 17722095-5 2007 Several dioxin-like PCB congeners were associated with increased risk of NHL, including dioxin-like PCB nos. Dioxins 88-94 pyruvate carboxylase Homo sapiens 100-103 17722095-5 2007 Several dioxin-like PCB congeners were associated with increased risk of NHL, including dioxin-like PCB nos. Dioxins 8-14 pyruvate carboxylase Homo sapiens 100-103 16823400-0 2007 Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States population. Dioxins 25-31 pyruvate carboxylase Homo sapiens 37-40 17712502-3 2007 Three dioxin-like PCB congeners had a mean value of TEQ of 0.24 pg-TEQ m(-3). Dioxins 6-12 pyruvate carboxylase Homo sapiens 18-21 17475378-6 2007 Here, we propose a scheme for developing relative potency estimates (REP) for the PCB congeners not considered in the TEF scheme used to assess the toxicity of coplanar and mono-ortho-PCBs and chlorinated dioxins and furans. Dioxins 205-212 pyruvate carboxylase Homo sapiens 82-85 17258273-0 2007 PCB and dioxin-like PCB in indoor air of public buildings contaminated with different PCB sources--deriving toxicity equivalent concentrations from standard PCB congeners. Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 17336149-5 2007 We present here first results on PCDD, PCDF and dioxin-like PCB (dl-PCB) concentrations in breast milk of 43 women living in Bavaria, Germany. Dioxins 48-54 pyruvate carboxylase Homo sapiens 60-63 17134732-10 2007 While the concentration of PCB increased significantly in the primary combustion chamber, the value of toxicity equivalency quantity for dioxin-like PCB decreased in the secondary combustion chamber and the flue gas treatment equipments. Dioxins 137-143 pyruvate carboxylase Homo sapiens 149-152 17207841-5 2007 After adding dioxin-like mono-ortho-PCBs the total PCB-TEQ concentrations ranged from 3.8 to 13.3 pg WHO-TEQ/g fat (mean value: 8.7 pg WHO-TEQ/g fat). Dioxins 13-19 pyruvate carboxylase Homo sapiens 36-39 17207842-17 2007 PCDD/F and dioxin-like PCB in human blood and milk from German mothers. Dioxins 11-17 pyruvate carboxylase Homo sapiens 23-26 17208274-11 2007 In conclusion, the 1999 PCB/dioxin incident was traceable in the plasma profiles (rise of the two specific PCDF congeners), but comparison of the results for both years indicates that the changes were too small to cause an adverse public health effect. Dioxins 28-34 pyruvate carboxylase Homo sapiens 24-27 17258273-0 2007 PCB and dioxin-like PCB in indoor air of public buildings contaminated with different PCB sources--deriving toxicity equivalent concentrations from standard PCB congeners. Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 17258273-0 2007 PCB and dioxin-like PCB in indoor air of public buildings contaminated with different PCB sources--deriving toxicity equivalent concentrations from standard PCB congeners. Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 17258273-1 2007 Data on dioxin-like PCB in indoor air of buildings with PCB-containing materials and on possible correlation between toxicity equivalent concentrations (TEQ) and levels of non-dioxin-like standard PCB is sparse. Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 17258273-2 2007 As part of a larger survey on indoor-air contamination with PCB, the connection between the concentration of standard PCB congeners and the dioxin-like toxicity expressed as TEQ was investigated. Dioxins 140-146 pyruvate carboxylase Homo sapiens 118-121 17258273-7 2007 Linear regression analysis between PCB and TEQ indicated that PCB 118 might be used to calculate the total TEQ of dioxin-like PCB and PCDD/PCDF. Dioxins 114-120 pyruvate carboxylase Homo sapiens 35-38 17258273-7 2007 Linear regression analysis between PCB and TEQ indicated that PCB 118 might be used to calculate the total TEQ of dioxin-like PCB and PCDD/PCDF. Dioxins 114-120 pyruvate carboxylase Homo sapiens 62-65 17258273-7 2007 Linear regression analysis between PCB and TEQ indicated that PCB 118 might be used to calculate the total TEQ of dioxin-like PCB and PCDD/PCDF. Dioxins 114-120 pyruvate carboxylase Homo sapiens 62-65 16765418-0 2006 PCDD/F and "Dioxin-like" PCB emissions from iron ore sintering plants in the UK. Dioxins 12-18 pyruvate carboxylase Homo sapiens 25-28 16962637-6 2007 Samples were analyzed for PCDD/F and twelve dioxin-like PCB congeners using high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS). Dioxins 44-50 pyruvate carboxylase Homo sapiens 56-59 16962637-7 2007 This study is very important since it is the first report on PCDDs/Fs and dioxin-like PCB contamination in human adipose tissue from Turkey. Dioxins 74-80 pyruvate carboxylase Homo sapiens 86-89 16597458-5 2006 Pregnant women residing in the study area >3 years had significantly higher PCDD (7.48 versus 5.13 pg-toxic equivalents [TEQ]/g-lipid) and dioxin-like PCB (6.70 versus 3.74 pg-TEQ/g-lipid) values as compared to those residing < or = 3 years. Dioxins 142-148 pyruvate carboxylase Homo sapiens 154-157 17256505-5 2006 PCBs clustered into seven groups, five of which contained a single "dioxin like" PCB, one contained lighter congeners (2-4 chlorines), and one contained heavy congeners (5-10 chlorines). Dioxins 68-74 pyruvate carboxylase Homo sapiens 0-3 16187124-6 2006 RESULTS: The lymphocytic 8-OH-dG level showed a negative association with the serum dioxin level (total value of TEQ-PCDD, PCDF, and Co-PCB). Dioxins 84-90 pyruvate carboxylase Homo sapiens 136-139 16955640-19 2006 PCB"s have similar properties to TCDD if they can exist in a planar configuration (dioxin-like PCB"s). Dioxins 83-89 pyruvate carboxylase Homo sapiens 0-3 16955640-19 2006 PCB"s have similar properties to TCDD if they can exist in a planar configuration (dioxin-like PCB"s). Dioxins 83-89 pyruvate carboxylase Homo sapiens 95-98 16955640-20 2006 The non-dioxin-like PCB"s always occur together with "dioxins"; their toxixty cannot be adequately determined although they occur in high concenrations. Dioxins 8-14 pyruvate carboxylase Homo sapiens 20-23 16955640-20 2006 The non-dioxin-like PCB"s always occur together with "dioxins"; their toxixty cannot be adequately determined although they occur in high concenrations. Dioxins 54-61 pyruvate carboxylase Homo sapiens 20-23 16451855-2 2006 In a 2002-2003 WHO exposure study, 13 pools of breast milk comprising samples from 316 primiparous women in Hong Kong in 2002 were analyzed by gas chromatography/mass spectrometry for 29 PCDD/F and dioxin-like PCB congeners. Dioxins 198-204 pyruvate carboxylase Homo sapiens 210-213 17009211-4 2006 Toxic equivalency factors have been established for the other PCDD, PCDF and dioxin-like PCB relative to TCDD, and the combined toxicity of a sample can be expressed as toxic equivalent (WHO-TEQ). Dioxins 77-83 pyruvate carboxylase Homo sapiens 89-92 16442144-0 2006 Dioxin and dioxin-like PCB exposure of non-breastfed Dutch infants. Dioxins 11-17 pyruvate carboxylase Homo sapiens 23-26 16442144-5 2006 From these data PCDD/F and dioxin-like PCB intake was calculated using PCDD/F and dioxin-like PCB concentrations of food products sampled in 1998/1999 in The Netherlands. Dioxins 27-33 pyruvate carboxylase Homo sapiens 39-42 16442144-5 2006 From these data PCDD/F and dioxin-like PCB intake was calculated using PCDD/F and dioxin-like PCB concentrations of food products sampled in 1998/1999 in The Netherlands. Dioxins 82-88 pyruvate carboxylase Homo sapiens 39-42 16442144-5 2006 From these data PCDD/F and dioxin-like PCB intake was calculated using PCDD/F and dioxin-like PCB concentrations of food products sampled in 1998/1999 in The Netherlands. Dioxins 82-88 pyruvate carboxylase Homo sapiens 94-97 16442144-6 2006 The long-term PCDD/F and dioxin-like PCB exposure of the infants was calculated using the statistical exposure model (STEM). Dioxins 25-31 pyruvate carboxylase Homo sapiens 37-40 16955640-1 2006 "Dioxins" are used to specify polychlorinated dibenzo-p-dioxins (PCDD), dibenzo-furanes (F) and dioxin-like polychlorinated biphenyls (PCB"s). Dioxins 1-8 pyruvate carboxylase Homo sapiens 135-138 16337987-5 2006 The medians of total non-dioxin-like PCB concentration were 1,835 and 1,033 ng g(-1) lipid in males and females, respectively. Dioxins 25-31 pyruvate carboxylase Homo sapiens 37-40 16337987-11 2006 Congeners 153, 138(+163), 180 and 170(+190) were the main contributors to total non-dioxin-like PCB concentrations. Dioxins 84-90 pyruvate carboxylase Homo sapiens 96-99 16263690-3 2005 Direct causal relationship between PCB and dioxin exposure and the observed detrimental effects on the immune system has yet to be fully established in humans. Dioxins 43-49 pyruvate carboxylase Homo sapiens 35-38 16506651-6 2006 Only a few Dutch studies have suggested that perinatal exposure to background level of PCB/dioxin confers immunity to allergy development. Dioxins 91-97 pyruvate carboxylase Homo sapiens 87-90 16182859-12 2005 Seven PCB congeners, (PCB 180, 153, 138, 170, 194, 118, and 156), including those at higher chlorination, were present in more than 30% of the subjects and contributed 99% of the total PCB levels, with a modest role of dioxin-like congeners. Dioxins 219-225 pyruvate carboxylase Homo sapiens 6-9 16047776-3 2005 Especially, certain dioxin-like coplanar PCB congeners (Co-PCBs), such as CB-77 and CB-105, whose source is commercial PCBs,were significantly higher in crows from the dumping site than those from the reference sites. Dioxins 20-26 pyruvate carboxylase Homo sapiens 41-44 16084869-6 2005 MAIN OUTCOME MEASURE(S): Assessment of dioxin (PCDD), furan (PCDF), and dioxin-like PCB serum concentrations (picograms toxic equivalent [TEQ]/g lipids). Dioxins 72-78 pyruvate carboxylase Homo sapiens 84-87 18969555-4 2004 These differences are more marked for the dioxin like PCB compounds (CALUX TEQ values are lower than WHO TEQ values) than for the dioxin compounds (CALUX TEQ values are higher than WHO TEQ values). Dioxins 42-48 pyruvate carboxylase Homo sapiens 54-57 15856391-0 2005 [Human biomonitoring investigations of organochlorine compounds -- PCB, DDE, HCB, beta- and gamma-HCH, PCDD/PCDF, Dioxin-like PCB"s and polybrominated biphenyl ethers]. Dioxins 114-120 pyruvate carboxylase Homo sapiens 126-129 15474616-2 2004 We have examined the effects of acute perfusion of 3,3",4,4"-tetrachlorobiphenyl (PCB 77), a coplanar, dioxin-like congener, on long-term potentiation (LTP) in the Schaffer collateral-CA1 and the mossy fiber-CA3 pathways in mouse hippocampus. Dioxins 103-109 pyruvate carboxylase Homo sapiens 82-85 15474616-6 2004 These observations provide evidence in support of the hypothesis that dioxin-like and non-dioxin-like PCB congeners are equally potent in causing the cognitive decrements seen in children exposed prenatally to PCBs. Dioxins 90-96 pyruvate carboxylase Homo sapiens 102-105 15667840-9 2005 The pattern of non-ortho and mono-ortho PCBs in the blood of children was similar to the pattern reported for mother"s milk, and PCB 126 and PCB 156 contributed about 70% to the toxicity of dioxin-like PCBs and about one-third to total TEQ including PCDD/PCDFs. Dioxins 190-196 pyruvate carboxylase Homo sapiens 129-132 18969556-8 2004 Using only an acidic silica column, the classical dioxin-like compounds investigated here (PCB, PCT, PBB, PCN, HCB) as well as the dioxins are collected and analyzed altogether in one fraction. Dioxins 50-56 pyruvate carboxylase Homo sapiens 91-94 18969556-10 2004 An acidic silica column combined with an activated carbon column allows the separation of PCDD/F and dioxin-like PCB in two different fractions, PBB 169 is completely eluted in the dioxin fraction and PBB 77 is distributed between the PCB and dioxin fraction. Dioxins 101-107 pyruvate carboxylase Homo sapiens 113-116 15330552-5 2004 Relative to some dioxin-like PCB congeners (mono-ortho PCB 105, 118, and 156; non-ortho PCB 77, 126, and 169), the intakes calculated varied from less than 0.001 to 0.74 pg of toxic equivalency values (TEQ) per kg of body weight per day. Dioxins 17-23 pyruvate carboxylase Homo sapiens 29-32 14659948-8 2004 The total dioxin/PCB level in milk, venous and cord serum can be well predicted by that in placenta through regression functions. Dioxins 10-16 pyruvate carboxylase Homo sapiens 17-20 14744201-3 2004 In 9-year-old children of the Rotterdam PCB--dioxin cohort, higher prenatal PCB levels were associated with longer response times (RTs), more variation in RTs, and lower scores on the Tower of London (TOL; Shallice, 1982). Dioxins 45-51 pyruvate carboxylase Homo sapiens 40-43 14744201-3 2004 In 9-year-old children of the Rotterdam PCB--dioxin cohort, higher prenatal PCB levels were associated with longer response times (RTs), more variation in RTs, and lower scores on the Tower of London (TOL; Shallice, 1982). Dioxins 45-51 pyruvate carboxylase Homo sapiens 76-79 14559260-0 2004 Concentrations of dioxin-like PCB congeners in unweathered Aroclors by HRGC/HRMS using EPA Method 1668A. Dioxins 18-24 pyruvate carboxylase Homo sapiens 30-33 14559260-2 2004 These Aroclor composition data should allow improved characterization and risk assessment of PCB contamination at hazardous waste sites, particularly for dioxin-like PCB congeners. Dioxins 154-160 pyruvate carboxylase Homo sapiens 166-169