PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1915853-5 1991 In this inside-out patch, intracellular GTP alone induced maximal channel reactivation, which was inhibited by GDP-beta S. These results suggest that 5-lipoxygenase metabolites of PAF-released arachidonic acid cause a persistent stimulation of GK but not the KACh channel itself, resulting in a receptor-independent activation of the KACh channel by GTP. guanosine 5'-O-(2-thiodiphosphate) 111-119 arachidonate 5-lipoxygenase Homo sapiens 150-164