PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10820229-4	2000	Here we report that in primary mouse bone marrow-derived mast cells activated by ionomycin or IgE/Ag, the proinflammatory mediator IL-1 (alpha or beta) up-regulated production of IL-3, IL-5, IL-6, and IL-9 as well as TNF, i.e., cytokines implicated in many inflammatory processes including those associated with allergies and helminthic infections.	Ionomycin	81-90	interleukin 1 complex	Mus musculus	131-150	
3262467-2	1988	When stimulated with suboptimal concentrations of ionomycin and phorbol myristate acetate (PMA), the immature subpopulation of Lyt2-,L3T4- (2-4-) thymocytes responded to exogenous, purified IL-1 in a dose-dependent manner.	Ionomycin	50-59	interleukin 1 complex	Mus musculus	190-194	
2574679-5	1989	Similarly to plastic-adsorbed antibodies, phorbol myristic acetate (PMA) or a combination of PMA and the calcium ionophore Ionomycin also induces secretion of growth factors without inducing proliferation, but in this case addition of IL 1 is ineffective in inducing AK-8 proliferation.	Ionomycin	123-132	interleukin 1 complex	Mus musculus	235-239	
7879702-3	1994	Human recombinant tumour necrosis factor-alpha (TNF-alpha) and the calcium ionophores A23187 and ionomycin induced a concentration-dependent increase of cell-associated IL-1 but failed to cause release of IL-1 at concentrations producing maximal stimulation of cell-associated IL-1.	Ionomycin	97-106	interleukin 1 complex	Mus musculus	169-173	
1688572-8	1990	The proliferative response induced in D10.G4 cells by IL-1 + ionomycin but not that induced by IL-1 + PMA was sensitive to inhibition by FK-506 and CsA.	Ionomycin	61-70	interleukin 1 complex	Mus musculus	54-58	
3090144-5	1986	In the presence of either suboptimal levels of phorbol ester (PMA) or Ionomycin, the addition of IL 1 resulted in up to an 80-fold enhancement in the amount of IL 2 secreted.	Ionomycin	70-79	interleukin 1 complex	Mus musculus	97-101	
3029093-6	1987	Both signal 1-type mediators, PHA and ionomycin, exerted pleiotropic effects at the concentrations required for synergy with signal 2-type mediators (IL1, TPA).	Ionomycin	38-47	interleukin 1 complex	Mus musculus	150-153	
3100060-6	1986	Il-1 required the simultaneous presence of ionomycin and TPA to have any demonstrable effect on T lymphocytes from spleen and on thymocytes.	Ionomycin	43-52	interleukin 1 complex	Mus musculus	0-4