PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8130263-1 1994 The release of arachidonic acid in A549 cells was stimulated in a time- and dose-dependent manner by the Ca2+ ionophore ionomycin (t1/2 = 4 min), thapsigargin (t1/2 = 8 min), bradykinin (t1/2 = 12 min, EC50 = 3 nM), and interleukin 1 alpha (t1/2 = 28 min, EC50 = 0.3 ng/ml). Ionomycin 120-129 kininogen 1 Homo sapiens 175-185 7683612-7 1993 At 100 nmol/l ionomycin intracellular calcium is increased from 114 +/- 17 nmol/l to 342 +/- 24 nmol/l (n = 9), a value within the range of intracellular calcium concentrations following application of bradykinin. Ionomycin 14-23 kininogen 1 Homo sapiens 202-212 1333726-6 1992 The calcium ionophores A23187 and ionomycin, similar to BK, caused a burst of PGE2 formation. Ionomycin 34-43 kininogen 1 Homo sapiens 56-58 11352510-5 2001 In the primed fibroblasts, ionomycin and thapsigargin mimicked the potentiating effect of bradykinin on the cyclooxygenase-2 mRNA expression. Ionomycin 27-36 kininogen 1 Homo sapiens 90-100 2108678-6 1990 The BK-stimulated Ca2+ transient, once having been completely inhibited by ionomycin (10(-6) M) in the presence of EGTA, was rapidly (within 2 min) recovered to the untreated level by replacing it with fresh medium containing 1.5 mM Ca2+. Ionomycin 75-84 kininogen 1 Homo sapiens 4-6 3661696-13 1987 The absence of extracellular Ca2+ during the interim period, or the pretreatment of cells with ionomycin in the absence of extracellular Ca2+, prevented the response of the cells to a second dose of bradykinin. Ionomycin 95-104 kininogen 1 Homo sapiens 199-209 10812056-7 2000 In the fibroblasts pretreated with interleukin-1beta, Ca(2+)-mobilizing reagents such as ionomycin and thapsigargin mimicked the potentiating effect of bradykinin on prostaglandin E(2) release. Ionomycin 89-98 kininogen 1 Homo sapiens 152-162