PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22272109-4 2011 Vanadyl sulfate effectively increased cellular GSH level and up-regulated mRNA and protein expression of a catalytic subunit of glutamate cysteine ligase (GCLC), which is involved in GSH synthesis. vanadyl sulfate 0-15 glutamate-cysteine ligase catalytic subunit Homo sapiens 155-159 22272109-5 2011 The induction of GCLC expression by vanadyl sulfate was found to be mediated by transcription factor erythroid transcription factor NF-E2 (Nrf2), which critically regulates GCLC by binding to the antioxidant response elements (AREs). vanadyl sulfate 36-51 glutamate-cysteine ligase catalytic subunit Homo sapiens 17-21 22272109-5 2011 The induction of GCLC expression by vanadyl sulfate was found to be mediated by transcription factor erythroid transcription factor NF-E2 (Nrf2), which critically regulates GCLC by binding to the antioxidant response elements (AREs). vanadyl sulfate 36-51 glutamate-cysteine ligase catalytic subunit Homo sapiens 173-177 22272109-9 2011 Taken together, these results suggest that the increase in GSH level by Jeju ground water is, at least in part, due to the effects of vanadyl sulfate via the Nrf2-mediated induction of GCLC. vanadyl sulfate 134-149 glutamate-cysteine ligase catalytic subunit Homo sapiens 185-189