PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27833015-6	2016	Our data showed that TMAO significantly triggered oxidative stress and activated TXNIP-NLRP3 inflammasome whereat inflammatory cytokines interleukin (IL)-1beta and IL-18 were released in a dose- and time-dependent manner, but endothelial nitric oxide synthase (eNOS) and production of nitric oxide (NO) were inhibited.	Nitric Oxide	238-250	interleukin 18	Homo sapiens	164-169	
21611811-0	2011	IL-12- and IL-18-mediated, nitric oxide-induced apoptosis in TNF-alpha-mediated osteoclastogenesis of bone marrow cells.	Nitric Oxide	27-39	interleukin 18	Homo sapiens	0-16	
11862579-3	2002	Interleukin (IL)-18, a newly discovered cytokine with pleiotropic activities, is known to induce proinflammatory cytokines, chemokines, nitric oxide, and prostaglandins.	Nitric Oxide	136-148	interleukin 18	Homo sapiens	0-19	
15190610-2	2004	IL-18 induces synthesis and release of proinflammatory cytokines, chemokines and nitric oxide.	Nitric Oxide	81-93	interleukin 18	Homo sapiens	0-5	
12076961-2	2002	Nitric oxide inhibits apoptosis and inflammation by S-nitrosylation of the active site cysteine of caspases, the central effector molecules of cell death as well as maturation of IL-1beta and IL-18.	Nitric Oxide	0-12	interleukin 18	Homo sapiens	192-197	
10880834-3	2000	In the present study, we show that even minor contamination with lymphoid cells of a pure population of macrophage-like cells (Raw 264.7) results in a marked production of nitric oxide after stimulation with both IL-12 and IL-18.	Nitric Oxide	172-184	interleukin 18	Homo sapiens	223-228	
9916738-5	1999	Studies on IL-18 effects on chondrocytes showed that it inhibits TGF-beta-induced proliferation and enhances nitric oxide production.	Nitric Oxide	109-121	interleukin 18	Homo sapiens	11-16