PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24498857-0	2014	Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2).	Resveratrol	0-11	solute carrier family 10 member 2	Homo sapiens	68-72	
24498857-0	2014	Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2).	Resveratrol	0-11	solute carrier family 10 member 2	Homo sapiens	74-81	
24498857-4	2014	In the present study, we investigated the possible involvement of ASBT in RSV-mediated cholesterol-lowering effects.	Resveratrol	74-77	solute carrier family 10 member 2	Homo sapiens	66-70	
24498857-5	2014	We demonstrate that RSV inhibits ASBT protein expression and function via a SIRT1 (sirtuin 1)-independent mechanism.	Resveratrol	20-23	solute carrier family 10 member 2	Homo sapiens	33-37	
24498857-7	2014	ASBT inhibition by RSV was reversed by proteasome inhibitors (MG-132 and lactacystin) and the ubiquitin inhibitor LDN57444, suggesting involvement of the ubiquitin-proteasome pathway.	Resveratrol	19-22	solute carrier family 10 member 2	Homo sapiens	0-4	
24498857-8	2014	Immunoprecipitation revealed high levels of ubiquitinated ASBT after RSV treatment.	Resveratrol	69-72	solute carrier family 10 member 2	Homo sapiens	58-62	
24498857-11	2014	Combined, our data indicate that RSV promotes ASBT degradation via the ubiquitin-proteasome pathway without requiring phosphorylation.	Resveratrol	33-36	solute carrier family 10 member 2	Homo sapiens	46-50	
24498857-12	2014	We conclude that regulation of ASBT expression by RSV may have clinical relevance with regard to the observed cholesterol-lowering effects of RSV.	Resveratrol	50-53	solute carrier family 10 member 2	Homo sapiens	31-35	
24498857-12	2014	We conclude that regulation of ASBT expression by RSV may have clinical relevance with regard to the observed cholesterol-lowering effects of RSV.	Resveratrol	142-145	solute carrier family 10 member 2	Homo sapiens	31-35