PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20030721-1 2010 We demonstrated that a yeast deletion mutant in IPT1 and SKN1, encoding proteins involved in the biosynthesis of mannosyldiinositolphosphoryl ceramides, is characterized by increased autophagy and DNA fragmentation upon nitrogen (N) starvation as compared with the single deletion mutants or wild type (WT). Nitrogen 220-228 inositolphosphotransferase Saccharomyces cerevisiae S288C 48-52