PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21666701-8 2011 RESULTS: Incubation of HCC cells under hypoxia (1% O2, 5% CO2, 94% N2) for 36 h significantly increased CA-IX expression level. Nitrogen 67-69 carbonic anhydrase 9 Homo sapiens 104-109 30445264-5 2019 Molecular docking of the designed hybrids in CA IX active site unveiled, as planned, the ability of N-alkylated and N-benzylated isatin moieties to accommodate in a wide hydrophobic pocket formed by T73, P75, P76, L91, L123 and A128, establishing strong van der Waals interactions. Nitrogen 100-101 carbonic anhydrase 9 Homo sapiens 45-50 30445264-5 2019 Molecular docking of the designed hybrids in CA IX active site unveiled, as planned, the ability of N-alkylated and N-benzylated isatin moieties to accommodate in a wide hydrophobic pocket formed by T73, P75, P76, L91, L123 and A128, establishing strong van der Waals interactions. Nitrogen 116-117 carbonic anhydrase 9 Homo sapiens 45-50 34436666-4 2022 In this review, we summarize existing literature data on PTMs of hCA IX and hCA XII, such as disulphide bond formation, phosphorylation, O-/N-linked glycosylation, acetylation and ubiquitination, highlighting, when possible, their specific role in cancer pathological processes. Nitrogen 140-141 carbonic anhydrase 9 Homo sapiens 65-71 18703501-7 2008 Mass spectrometry experiments showed that CA IX contains an intramolecular disulfide bridge (Cys(119)-Cys(299)) and a unique N-linked glycosylation site (Asn(309)) that bears high mannose-type glycan structures. Nitrogen 125-126 carbonic anhydrase 9 Homo sapiens 42-47 16942027-4 2006 The same interactions were preserved in the adduct with hCA IX, but in addition, a hydrogen bond between the SH moiety of the inhibitor and the amide nitrogen of Gln67 was evidenced, which may explain the almost 2 times more effective inhibition of the tumor-associated isozyme over the cytosolic isoform. Nitrogen 150-158 carbonic anhydrase 9 Homo sapiens 56-62