PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32221363-8 2020 Serum adiponectin level was inversely associated with eGFR (p < 0.001) and positively correlated with urine albumin-creatinine ratio. Creatinine 116-126 adiponectin, C1Q and collagen domain containing Homo sapiens 6-17 34242326-8 2021 Regarding laboratory data, adiponectin level was associated with creatinine, and chemerin level was associated with creatinine, albumin, and erythrocyte sedimentation rate (ESR). Creatinine 65-75 adiponectin, C1Q and collagen domain containing Homo sapiens 27-38 35097010-9 2021 Subgroup analyses demonstrated that the association of high serum adiponectin with increased risk of fatal and non-fatal CV events is not modified by age, gender, history of diabetes, estimated glomerular filtration rate (eGFR), or spot urine albumin-to-creatinine ratio (ACR). Creatinine 254-264 adiponectin, C1Q and collagen domain containing Homo sapiens 66-77 33558151-5 2021 We evaluated the relationships between the creatinine-adjusted urinary total-ADPN and HMW-ADPN, albumin (UACR) and liver-type fatty acid binding protein (L-FABP) at baseline and the 2-year change of the estimated glomerular filtration rate (DeltaeGFR). Creatinine 43-53 adiponectin, C1Q and collagen domain containing Homo sapiens 77-81 33141880-7 2021 In a cross-sectional analysis, adiponectin was positively associated with urinary albumin:creatinine ratio at baseline (P = 0.009). Creatinine 90-100 adiponectin, C1Q and collagen domain containing Homo sapiens 31-42 31956139-8 2020 Age- and sex-adjusted ADPN levels were positively associated with heart rate, QTc interval, left ventricular mass index, and creatinine but negatively associated with left ventricular ejection fraction, waist circumference, current smoking, total cholesterol, triglycerides, low-density lipoprotein cholesterol, albumin, and estimated glomerular filtration rate. Creatinine 125-135 adiponectin, C1Q and collagen domain containing Homo sapiens 22-26 31245009-6 2019 Results: The urinary adiponectin levels were 14.88+-3.16 (ng/mg creatinine, mean+-SEM) for patients with DM, and 3.06+-0.33 (ng/mg creatinine) for normal subjects. Creatinine 64-74 adiponectin, C1Q and collagen domain containing Homo sapiens 21-32 29287218-11 2018 Serum adiponectin level was inversely associated with body mass index, eGFR, log-transformed C-reactive protein, and positively with Charlson comorbidity index, urine protein to creatinine ratio, and high density lipoprotein cholesterol. Creatinine 178-188 adiponectin, C1Q and collagen domain containing Homo sapiens 6-17 29199440-3 2018 Results The urinary adiponectin concentrations in patients with diabetes (3.3 +- 10.7 ng/mg creatinine) were significantly higher than those in obese subjects (0.54 +- 0.44; P < 0.01) and healthy subjects (0.46 +- 0.42; P < 0.001). Creatinine 92-102 adiponectin, C1Q and collagen domain containing Homo sapiens 20-31 24467624-7 2016 Also, urinary adiponectin/creatinine ratio was significantly higher in the former group (221.72 +- 414.58 vs. 19.99 +- 41.19, P = 0.019). Creatinine 26-36 adiponectin, C1Q and collagen domain containing Homo sapiens 14-25 27514393-7 2017 RESULTS: Increasing quartiles of serum adiponectin levels were associated with women, lower eGFRs and body mass indices, and higher urinary albumin-creatinine ratios. Creatinine 148-158 adiponectin, C1Q and collagen domain containing Homo sapiens 39-50 28752734-7 2017 Furthermore, there was a significant positive correlation between adiponectin and serum creatinine &blood urea levels in both conservative and dialysis groups with P <0.05. Creatinine 88-98 adiponectin, C1Q and collagen domain containing Homo sapiens 66-77 24469713-10 2014 We observed also that the decrease of the serum Adiponectin level was accompanied by an insulin resistance, albuminuria, as well as an increase of serum creatinine. Creatinine 153-163 adiponectin, C1Q and collagen domain containing Homo sapiens 48-59 26445954-6 2016 Univariate linear regression analysis showed that the serum adiponectin concentrations were correlated with age, the albumin-to-creatinine ratio, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol, whereas they were negatively correlated with body mass index, the estimated glomerular filtration rate, and serum albumin and triglyceride levels. Creatinine 128-138 adiponectin, C1Q and collagen domain containing Homo sapiens 60-71 27493857-7 2015 The pilot study showed that the urinary adiponectin levels, which were corrected by the creatinine concentration, were 0.73+-0.50 (ng/mg creatinine, N=6) for healthy subjects, versus 12.02+-3.85 (ng/mg creatinine, N=3) for patients with diabetes mellitus (DM). Creatinine 88-98 adiponectin, C1Q and collagen domain containing Homo sapiens 40-51 27493857-7 2015 The pilot study showed that the urinary adiponectin levels, which were corrected by the creatinine concentration, were 0.73+-0.50 (ng/mg creatinine, N=6) for healthy subjects, versus 12.02+-3.85 (ng/mg creatinine, N=3) for patients with diabetes mellitus (DM). Creatinine 137-147 adiponectin, C1Q and collagen domain containing Homo sapiens 40-51 27493857-7 2015 The pilot study showed that the urinary adiponectin levels, which were corrected by the creatinine concentration, were 0.73+-0.50 (ng/mg creatinine, N=6) for healthy subjects, versus 12.02+-3.85 (ng/mg creatinine, N=3) for patients with diabetes mellitus (DM). Creatinine 137-147 adiponectin, C1Q and collagen domain containing Homo sapiens 40-51 26115618-7 2015 Serum adiponectin (baseline mean 14.3 +- 6.6 mug/ml) and urine adiponectin:creatinine (Uadp/cr) (baseline mean 126.8 +- 178.9 mug/ml) directly correlated with proteinuria at all time points (r = 0.37-0.81; all p < 0.05). Creatinine 75-85 adiponectin, C1Q and collagen domain containing Homo sapiens 63-74 20045535-4 2010 Multiple regression analysis adjusted for age, duration of diabetes, sex, body height, body weight, waist circumference, serum creatinine, and hemoglobin A(1c) showed that serum total adiponectin was still significantly and positively correlated with percentage change in FN-BMD (r = 0.65, P < .01). Creatinine 127-137 adiponectin, C1Q and collagen domain containing Homo sapiens 184-195 24147206-7 2013 RESULTS: In models of multiple linear regression, sex hormone-binding globulin, fasting insulin (inverse) and, in men, age were significant independent covariates of serum adiponectin which further tended in women to be positively associated with serum creatinine. Creatinine 253-263 adiponectin, C1Q and collagen domain containing Homo sapiens 172-183 24364044-10 2013 Serum adiponectin correlated positively with dialysate to plasma (D/P) creatinine ratio and ultrafiltration in PET test. Creatinine 71-81 adiponectin, C1Q and collagen domain containing Homo sapiens 6-17 23574756-5 2013 After adjustment for percentage body fat, HDL cholesterol and serum leptin, hemoglobin and creatinine-based eGFR remained independent predictors of adiponectin (standardized beta coefficient=-0.248, p<0.0001, and -0.101, p=0.03, respectively). Creatinine 91-101 adiponectin, C1Q and collagen domain containing Homo sapiens 148-159 21993769-0 2012 Low plasma adiponectin levels predict increased urinary albumin/creatinine ratio in type 2 diabetes patients. Creatinine 64-74 adiponectin, C1Q and collagen domain containing Homo sapiens 11-22 21992860-7 2012 RESULTS: Serum adiponectin was significantly elevated in complicated diabetes (10.3 +- 5.9 pg/dL) as compared to the controls (6.5 +- 3.7 pg/dL) (P<0.01), and correlated directly with HbA1c (P<0.05) and creatinine (P<0.001). Creatinine 209-219 adiponectin, C1Q and collagen domain containing Homo sapiens 15-26 22483466-13 2012 Multivariate analysis revealed that gender, body weight, serum creatinine, triglyceride, and HDL cholesterol were associated with APN level. Creatinine 63-73 adiponectin, C1Q and collagen domain containing Homo sapiens 130-133 21933002-9 2012 Adiponectin was correlated negatively with CIMT (r=-0.24, P=0.03), age (r=-0.30, P=0.02), BMI (r=-0.33, P=0.02), waist-to-hip ratio (WHR) (r=-0.38, P=0.01) and positively with creatinine (r=0.44, P=0.004). Creatinine 176-186 adiponectin, C1Q and collagen domain containing Homo sapiens 0-11 21933002-12 2012 Multivariate analysis revealed resistin and creatinine to be independent predictors of CIMT among adiponectin, leptin, resistin, WHR, glycosylated hemoglobin (HbA1c), and creatinine. Creatinine 44-54 adiponectin, C1Q and collagen domain containing Homo sapiens 98-109 21545814-10 2011 Single regression analyses performed in all specified groups revealed significant associations between adiponectin and estimated creatinine clearance, however a multiple regression model revealed that insulin resistance had the strongest association with adiponectin within all the groups. Creatinine 129-139 adiponectin, C1Q and collagen domain containing Homo sapiens 103-114 20825465-11 2011 Using the same model, log leptin and log adiponectin presented positive and negative associations, respectively with LTE(4) /creatinine in urine. Creatinine 125-135 adiponectin, C1Q and collagen domain containing Homo sapiens 41-52 19359150-3 2010 Plasma ADPN levels were directly correlated with age, HDL-C and creatinine, and inversely with BMI, triglycerides and glomerular filtration rate (GFR). Creatinine 64-74 adiponectin, C1Q and collagen domain containing Homo sapiens 7-11 19359150-4 2010 Multiple regression analysis identified plasma creatinine and HDL as the independent factors associated with ADPN plasma levels. Creatinine 47-57 adiponectin, C1Q and collagen domain containing Homo sapiens 109-113 19509019-8 2009 Urinary adiponectin was significantly increased in type 2 diabetes (7.68 +/- 14.26 vs. control subjects: 2.91 +/- 3.85 microg/g creatinine, P = 0.008). Creatinine 128-138 adiponectin, C1Q and collagen domain containing Homo sapiens 8-19 19907101-7 2009 Triglyceride and serum creatinine levels were associated with HMW adiponectin in men only. Creatinine 23-33 adiponectin, C1Q and collagen domain containing Homo sapiens 66-77 19052467-5 2009 The plasma adiponectin concentration as a whole was positively correlated with serum high-density lipoprotein cholesterol and negatively with serum creatinine and waist circumference. Creatinine 148-158 adiponectin, C1Q and collagen domain containing Homo sapiens 11-22 19200219-8 2009 Low creatinine clearance was associated with higher plasma adiponectin (R=-0.26, p = 0.01). Creatinine 4-14 adiponectin, C1Q and collagen domain containing Homo sapiens 59-70 18949730-8 2008 There was also a positive trend between plasma adiponectin levels and the ratios of dialysate to plasma creatinine concentration (D/P Cr). Creatinine 104-114 adiponectin, C1Q and collagen domain containing Homo sapiens 47-58 18593765-8 2008 After controlling for matching factors, adjustment for waist to hip ratio, hypertension, smoking, alcohol, low-density lipoprotein cholesterol, creatinine, and leptin revealed a modestly increased risk of incident CHD with adiponectin concentrations at the upper end [odds ratio = 1.37 (quintile 5 vs. 1-4), 95% confidence interval 1.02-1.84]. Creatinine 144-154 adiponectin, C1Q and collagen domain containing Homo sapiens 223-234 18230826-7 2008 HMW adiponectin and total adiponectin correlated positively with creatinine and negatively with fasting insulin in univariate and multivariate analyses. Creatinine 65-75 adiponectin, C1Q and collagen domain containing Homo sapiens 4-15 18230826-7 2008 HMW adiponectin and total adiponectin correlated positively with creatinine and negatively with fasting insulin in univariate and multivariate analyses. Creatinine 65-75 adiponectin, C1Q and collagen domain containing Homo sapiens 26-37 18721492-12 2008 We found a statistically significant negative correlation between adiponectin and creatinine (r=-0.26; p=0.011). Creatinine 82-92 adiponectin, C1Q and collagen domain containing Homo sapiens 66-77 18721492-17 2008 Adiponectin level correlated negatively with creatinine level end microalbuminuria. Creatinine 45-55 adiponectin, C1Q and collagen domain containing Homo sapiens 0-11 17490776-7 2007 Serum adiponectin positively correlated with serum creatinine and negatively correlated with 1/creatinine. Creatinine 51-61 adiponectin, C1Q and collagen domain containing Homo sapiens 6-17 17490776-7 2007 Serum adiponectin positively correlated with serum creatinine and negatively correlated with 1/creatinine. Creatinine 95-105 adiponectin, C1Q and collagen domain containing Homo sapiens 6-17 17443034-5 2007 Since the serum adiponectin level is strongly affected by renal function, we classified the patients by creatinine clearance. Creatinine 104-114 adiponectin, C1Q and collagen domain containing Homo sapiens 16-27 17363678-9 2007 In all subjects (n = 29), adiponectin mRNA was related (P < 0.05) negatively with TBARS after adjusting for plasma C-reactive protein (CRP) or CRP and creatinine. Creatinine 154-164 adiponectin, C1Q and collagen domain containing Homo sapiens 26-37 17425653-4 2007 Plasma concentrations of TNF-alpha, IL-6, IL-10, IL-18, CCL2, CXCL8, CXCL9, CXCL10 and adiponectin exhibited significant positive correlation with urine albumin : creatinine ratio in DN patients. Creatinine 163-173 adiponectin, C1Q and collagen domain containing Homo sapiens 87-98 17443034-6 2007 RESULTS: Multiple regression analysis showed the associations of adiponectin with creatinine clearance (p<0.001), BMI (p<0.001), serum triglyceride (p=0.001) and urinary protein excretion (p=0.001). Creatinine 82-92 adiponectin, C1Q and collagen domain containing Homo sapiens 65-76 17443034-7 2007 We observed a positive relation of adiponectin with urinary protein excretion and an inverse relation of adiponectin with creatinine clearance, serum triglyceride, and BMI. Creatinine 122-132 adiponectin, C1Q and collagen domain containing Homo sapiens 105-116 16804063-5 2006 Like serum total adiponectin, HMW adiponectin correlated positively with HDL cholesterol and negatively with triglyceride, insulin sensitivity, creatinine clearance, and circulating inflammatory markers. Creatinine 144-154 adiponectin, C1Q and collagen domain containing Homo sapiens 34-45 16966829-7 2006 Urinary adiponectin levels were also positively correlated with serum creatinine (r = 0.729, P<0.0001), urinary albumin (r = 0.799, P<0.0001), urinary NAG (r = 0.701, P<0.0001), and urinary MCP-1 (r = 0.801, P<0.0001) levels in all diabetic patients. Creatinine 70-80 adiponectin, C1Q and collagen domain containing Homo sapiens 8-19 16966829-8 2006 Multiple linear regression analysis showed that serum creatinine and urinary adiponectin levels were independently associated with serum adiponectin levels (r(2) = 0.522), and that serum creatinine, urinary NAG, urinary MCP-1, and serum adiponectin levels were independent determinants of urinary adiponectin levels (r(2) = 0.851). Creatinine 54-64 adiponectin, C1Q and collagen domain containing Homo sapiens 137-148 16966829-8 2006 Multiple linear regression analysis showed that serum creatinine and urinary adiponectin levels were independently associated with serum adiponectin levels (r(2) = 0.522), and that serum creatinine, urinary NAG, urinary MCP-1, and serum adiponectin levels were independent determinants of urinary adiponectin levels (r(2) = 0.851). Creatinine 54-64 adiponectin, C1Q and collagen domain containing Homo sapiens 137-148 16966829-8 2006 Multiple linear regression analysis showed that serum creatinine and urinary adiponectin levels were independently associated with serum adiponectin levels (r(2) = 0.522), and that serum creatinine, urinary NAG, urinary MCP-1, and serum adiponectin levels were independent determinants of urinary adiponectin levels (r(2) = 0.851). Creatinine 54-64 adiponectin, C1Q and collagen domain containing Homo sapiens 137-148 16709438-7 2006 Changes in ADPN correlated negatively with leptin, insulin resistance, albumin, C-reactive protein, and creatinine clearance. Creatinine 104-114 adiponectin, C1Q and collagen domain containing Homo sapiens 11-15 15897361-6 2005 A significant association between smoking and low adiponectin level was also confirmed in multiple regression analysis including age, body mass index, hypertension, diabetes, hyperlipidemia, and creatinine clearance (never-smokers 6.5+/-0.4 microg/mL; past smokers 5.6+/-0.3 microg/mL; current smokers 5.2+/-0.4 microg/mL; F=4.52; P=0.01). Creatinine 195-205 adiponectin, C1Q and collagen domain containing Homo sapiens 50-61 16022092-11 2005 Interestingly, we found a negative correlation between log ADPN and creatinine levels among the CPD patients (r = -0.54, p < 0.05). Creatinine 68-78 adiponectin, C1Q and collagen domain containing Homo sapiens 59-63 16022092-13 2005 Creatinine and low-density lipoprotein levels could account for 54% of the total variation in ADPN levels. Creatinine 0-10 adiponectin, C1Q and collagen domain containing Homo sapiens 94-98 16022092-14 2005 CONCLUSION: Among pediatric CPD patients, serum levels of the anti-atherogenic protein, ADPN, were inversely associated with creatinine. Creatinine 125-135 adiponectin, C1Q and collagen domain containing Homo sapiens 88-92 15897668-9 2005 Adiponectin correlated significantly, in univariate analysis, with CD146 (r = 0.29, p = 0.009), thrombomodulin (r = 0.37, p = 0.001), protein Z (r = -0.25, p = 0.03), BMI (r = -0.26, p = 0.047), serum creatinine (r = 0.26, p = 0.02) and urea (r = 0.38, p = 0.001). Creatinine 201-211 adiponectin, C1Q and collagen domain containing Homo sapiens 0-11 15585515-11 2005 A positive relationship was also found between plasma adiponectin and the urinary albumin/creatinine ratio (P = 0.007). Creatinine 90-100 adiponectin, C1Q and collagen domain containing Homo sapiens 54-65 15239024-10 2004 3) Adiponectin levels are dependent on renal function at a creatinine clearance < 45 ml/min. Creatinine 59-69 adiponectin, C1Q and collagen domain containing Homo sapiens 3-14 15957550-7 2005 Moreover, positive correlations between urinary adiponectin levels and albumin-to-creatinine ratios were observed in IgA-nephropathy (R2=0.53, P<0.01) and diabetic nephropathy patients (R2=0.61, P<0.01), but not in control subjects. Creatinine 82-92 adiponectin, C1Q and collagen domain containing Homo sapiens 48-59 15451906-8 2004 Serum adiponectin concentration correlated negatively with the 24-h LF-to-HF ratio (r = -0.343, P = 0.0009) and creatinine clearance (r = -0.411, P < 0.0001). Creatinine 112-122 adiponectin, C1Q and collagen domain containing Homo sapiens 6-17 15292342-5 2004 Both urinary albumin to creatinine ratio (ACR) and serum creatinine were positively correlated with adiponectin (Spearman"s r = 0.43; P < 0.0001, and r = 0.37; P < 0.0001, respectively) in diabetic subjects. Creatinine 24-34 adiponectin, C1Q and collagen domain containing Homo sapiens 100-111 15292342-5 2004 Both urinary albumin to creatinine ratio (ACR) and serum creatinine were positively correlated with adiponectin (Spearman"s r = 0.43; P < 0.0001, and r = 0.37; P < 0.0001, respectively) in diabetic subjects. Creatinine 57-67 adiponectin, C1Q and collagen domain containing Homo sapiens 100-111 14592564-8 2003 In the CAD group plasma adiponectin concentration correlated with levels of creatinine (r=0.56; p<0.001), HDL cholesterol (r=0.24; p<0.05), BMI (r=-0.33; p<0.001), glucose (r=-0.22; p<0.05) and triglycerides (r=-0.25; p<0.05). Creatinine 76-86 adiponectin, C1Q and collagen domain containing Homo sapiens 24-35 12455716-7 2002 In hypertensive patients, plasma ADPN was inversely related to creatinine clearance and tended to be inversely related to serum insulin (r= -0.27) and HOMA-R index (r= -0.24). Creatinine 63-73 adiponectin, C1Q and collagen domain containing Homo sapiens 33-37 12455716-8 2002 The relationship between plasma ADPN and renal function was confirmed in a multiple regression analysis which showed that creatinine clearance was the only independent predictor of plasma ADPN. Creatinine 122-132 adiponectin, C1Q and collagen domain containing Homo sapiens 32-36 12455716-8 2002 The relationship between plasma ADPN and renal function was confirmed in a multiple regression analysis which showed that creatinine clearance was the only independent predictor of plasma ADPN. Creatinine 122-132 adiponectin, C1Q and collagen domain containing Homo sapiens 188-192 12050247-8 2002 The slightly positive correlation between adiponectin and age, blood urea nitrogen, or creatinine levels was also observed (all P < 0.001). Creatinine 87-97 adiponectin, C1Q and collagen domain containing Homo sapiens 42-53